摘要
卵泡发育可分为原始卵泡、生长卵泡和成熟卵泡3个阶段,其中生长卵泡阶段又可分为窦前卵泡、窦卵泡及排卵前卵泡.卵泡发育过程受到来自卵母细胞、颗粒细胞、膜细胞、基质、血管等多方的因素相互作用,变化丰富、复杂,过程中任何一分子或信号通路的异常即有可能引起卵泡发育的障碍.本文就影响生长卵泡发育阶段的相关因素进行梳理与总结.
The process of follicular development can be divided into primordial follicle,growing follicules,and mature follicle.The phase of growing follicles can be divided into pre-antral follicle,antral follicle and pre-ovulatory follicle.Many factors from oocytes,granulosa cells,theca cells,matrix,blood vessels and so on have been changed richly with complex interactions.Any abnormal molecules or signaling pathways during the above process may cause problems of follicle development.This article will summarize the related factors of growing follicular phase.
作者
闫艺之
王颖
Yan Yizhi;Wang Ying(Peking University the Thrid Hospital Reproductive Center,Beijing 100191,China)
出处
《中华生殖与避孕杂志》
CAS
CSCD
北大核心
2020年第1期69-77,共9页
Chinese Journal of Reproduction and Contraception
关键词
生长卵泡
转化生长因子-β超家族
优势卵泡
卵巢血管化
内分泌腺性血管内皮生成因子
Growing follice
Transforming growth factor β super family
Dominant follicle
Ovarian vascularization
Endocrine gland-derived vascular endothelial growth factor
作者简介
通信作者:王颖,Email:wangying02114@bjmu.edu.cn,电话:+86-13911688652。
