摘要
目的探讨加味补血汤治疗气虚血瘀型缺血性脑中风35例临床效果。方法纳入70例气虚血瘀型中风患者作为研究对象,随机抽签分为两组,每组35例。对照组行西医常规治疗,治疗组在对照组基础上以加味补血汤进行治疗。比较两组治疗效果及血小板、氧化应激指标变化。结果治疗组治疗显效率显著高于对照组(P<0.05)。治疗组治疗结束时、治疗1月及治疗后2月时NIHSS评分显著低于对照组(P<0.05)。治疗组治疗后MDA、ox-LDL水平与治疗前及对照组治疗后对比显著降低,且治疗组治疗后GSH-Px水平与治疗前及对照组治疗后对比显著提高,差异有统计学意义(P<0.05)。治疗组治疗后MPV、PAgT水平与治疗前及对照组治疗后对比显著降低,且治疗组治疗后PLT水平与治疗前及对照组治疗后对比显著提高,差异有统计学意义(P<0.05)。结论加味补血汤治疗气虚血瘀型中风疗效显著,有助于保护脑神经功能、增强血小板功能,降低血清氧化应激水平。
Objective To investigate the clinical effect of Modified Buxue Decoction in treating 35 cases of ischemic cerebral stroke with qi deficiency and blood stasis. Methods 70 patients with stroke of qi deficiency and blood stasis were randomly divided into two groups, 35 in each group. The control group was treated with conventional western medicine, and the treatment group was treated with Modified Buxue Decoction on the basis of the control group. The therapeutic effect and the changes of platelet and oxidative stress were compared between the two groups. Results the effective rate of the treatment group was significantly higher than that of the control group(P < 0.05). The NIHSS score of the treatment group was significantly lower than that of the control group at the end of the treatment(P < 0.05). The levels of MDA and Ox-LDL after treatment in the treatment group were significantly lower than those before treatment, and also significantly lower than those after treatment in the control group, and the levels of GSH-Px in the treatment group were significantly higher than those before treatment and after the treatment in the control group. The difference was statistically significant(P <0.05). The levels of MPV and PAgT in the treatment group after treatment were significantly lower than those before the treatment and also significantly lower than those after treatment in the control group, while the levels of PLT in the treatment group were significantly higher than those before the treatment and also significantly higher than those after treatment in the control group. The difference was statistically significant(P <0.05). Conclusion Modified Buxue Decoction has a significant therapeutic effect on stroke of qi deficiency and blood stasis, which is helpful to protect brain nerve function, enhance platelet function and reduce serum oxidative stress.
作者
王博
Wang Bo(TCM Hospital of Huazhou District,Weinan China,714100)
出处
《现代中医药》
CAS
2020年第2期62-65,共4页
Modern Chinese Medicine
关键词
加味补血汤
溶栓
气虚血瘀
中风
Modified Buxue Decoction
Thrombolysis
Qi deficiency and blood stasis
Stroke
