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食源性免疫活性肽的筛选策略及作用机制研究进展 被引量:8

Progresses of the screening strategies and the effect mechanism researches of food-derived immunopeptides
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摘要 文章综述了目前国内外对食源性免疫活性肽的筛选策略,强调计算科学在筛选中的应用前景。通过探讨食源性免疫活性肽作用的分子机理及其研究现状,提出了未来的研究新思路:结合多组学、生物信息学、细胞试验及动物试验,深入探讨食源性免疫活性肽作用的分子机理。 The global undergoing strategies of screening the foodderived immunopeptides were summarized in this review,and the prospective using of computational science was emphasized.Moreover,the research background of the molecular mechanism of the food-derive immunopeptides was reviewed,and a new research strategy was also proposed,i.e.combining the multiomics,bioinformatics,and cellular and animal experiments to investigate their molecular mechanism.
作者 文李 NIYOKWIZERA Isaac 刘步青 许宙 陈茂龙 程云辉 WEN Li;NIYOKWIZERA Isaac;LIU Bu-qing;XU Zhou;CHEN Mao-long;CHENG Yun-hui(College of Chemical and Food Engineering,Changsha University of Science and Technology,Changsha,Hunan 410114,China)
出处 《食品与机械》 北大核心 2020年第2期7-11,37,共6页 Food and Machinery
基金 国家自然科学基金面上项目(编号:31972077) 湖南省自然科学基金面上项目(编号:2018JJ2423) 湖南省协同创新中心项目(编号:15xtcx001) 长沙理工大学“双一流”科学研究国际合作拓展项目(编号:2018IC20)。
关键词 食源性 免疫活性肽 计算科学 筛选 免疫调控分子机理 food-derived immunopeptides computational sciences screening molecular mechanism of immuno-regulation
作者简介 文李,女,长沙理工大学副教授,硕士生导师,博士;通信作者:程云辉(1964-),女,长沙理工大学教授,硕士生导师,博士。E-mail:chengyh6488@sina.com。
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