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云南白药保险子外敷联合[牙合]垫治疗颞下颌关节紊乱病的临床研究 被引量:4

Clinical Study of Yunnan Baiyao Baoxianzi Topical Application Combined with Occlusal Appliance for Temporomandibular Disorders
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摘要 目的观察云南白药保险子关节区局部外敷联合[牙合]垫治疗颞下颌关节紊乱病(TMD)关节区疼痛和张口受限的临床疗效。方法选择2019年1-9月在浙江大学医学院附属第二医院综合牙科就诊的68例TMD患者,随机分为试验组(云南白药保险子外敷联合[牙合]垫治疗)32例,对照组(安慰剂外敷联合[牙合]垫治疗)36例。以临床症状消失或明显改善为治疗结束,记录患者治疗时间。治疗前、治疗1个月及治疗后利用视觉类比评分(VAS)评价关节区疼痛程度,记录张口程度。结果最终试验组28例患者完成研究,对照组34例患者完成研究。试验组(13.44±4.46)与对照组(13.53±6.47)治疗时间(w)比较,差异无统计学意义(P>0.05)。与治疗前比较,两组治疗1个月及治疗后VAS下降,张口程度增加(P<0.05)。与本组治疗1个月比较,两组治疗后VAS下降,张口程度增加(P<0.05),对照组治疗后VAS缓解速率下降(P<0.05)。与对照组同期比较,试验组治疗1个月及治疗后VAS下降,VAS缓解速率及张口程度增加(P<0.05)。结论云南白药保险子外敷联合[牙合]垫治疗可有效改善TMD关节区疼痛和张口受限。 Objective To observe the effects of Yunnan Baiyao Baoxianzi(BXZ) topical application combined with occlusal appliance for joint pain and mouth opened limiting of temporomandibular joint disorders(TMD) patients. Methods Totally 68 TMD patients who visited the department of general dentistry, the Second Affiliated Hospital of Medical School of Zhejiang University were randomly assigned to experimental group(32 cases) and control group(36 cases). The experimental group was given occlusal appliance combined with BXZ topical application. The control group was given occlusal appliance combined with placebo topical application. The disappearance or significant improvement of clinical symptoms was the end of treatment. The time of treatment was recorded. The joint pain was evaluated by visual analogue scale(VAS), the degree of mouth opening was recorded before treatment, 1 month treatment and after treatment. Results Finally 28 cases in experimental group, 34 cased in control group completed the study. There was no statistical differnce between the treatment time of experimental group [(13.44±4.46)weeks] and control group [(13.53±6.47)weeks]. Compared with before treatment, VAS decreased, degree of mouth opening increased at 1 month treatment in two groups(P<0.05). Compared with 1 month treatment, VAS decreased, degree of mouth opening increased after treatment in two groups(P<0.05), VAS ease rate decreased after treatment in control group(P<0.05). Compared with same time in control group, VAS decreased, VAS ease rate and degree of mouth opening increased at 1 month treatment and after treatment in experimental group(P<0.05). Conclusion BXZ topical application combined with occlusal appliance can alleviate joint pain and mouth opened limiting of TMD patients.
作者 杨璐铭 葛子瑜 俞婷婷 章燕珍 YANG Lu-ming;GE Zi-yu;YU Ting-ting;ZHANG Yan-zhen(Department of General Dentistry,The Second Affiliated Hospital of Medical School of Zhejiang University,Hangzhou(310000))
出处 《中国中西医结合杂志》 CAS CSCD 北大核心 2020年第3期309-312,共4页 Chinese Journal of Integrated Traditional and Western Medicine
基金 浙江省中医药科技计划项目(No.2018ZA075)。
关键词 颞下颌关节紊乱病 [牙合]垫 云南白药 保险子 temporomandibular disorder occlusal appliance YunnanBaiyao Baoxianzi
作者简介 通讯作者:章燕珍,Tel:0571-89713393,E-mail:2191004@zju.edu.cn。
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