摘要
房颤患者经皮冠状动脉介入术后需要通过抗凝联合双联抗血小板的三联抗栓治疗,三联抗栓方案在预防血栓的同时也增加了出血风险。本文通过回顾近年指南关于三联抗栓方案的推荐,结合最新循证研究,分析讨论抗栓方案中双联是否可以取代三联,如何确定最优疗程,抗凝及抗血小板药物的选择,支架类型的选择及患者性别影响等方面的内容。以期寻求最优抗栓策略,做到精准个体化治疗。
Atrial fibrillation patients undergoing percutaneous coronary intervention often need to be treated with oral anticoagulation plus dual antiplatelet therapy.However,this treatment has a higher risk of bleeding in the prevention of thrombosis.To achieve personalized treatment goals,this review analyzed and discussed whether double therapy may replace triple antithrombotic therapy,the best duration of antithrombotic therapy,choice of anticoagulants and antiplatelet drugs,type of stent,gender influence,etc,based on reviewing guidelines for triple antithrombotic therapy and the associated new clinical studies.
作者
赵静
王育苗
ZHAO Jing;WANG Yu-miao(Binhai New Area Hospital of Tianjin Traditional Chinese Medicine,Tianjin 300450)
出处
《中南药学》
CAS
2020年第2期270-275,共6页
Central South Pharmacy
关键词
房颤
经皮冠状动脉介入术
三联抗栓
口服抗凝药
抗血小板药物
atrial fibrillation
percutaneous coronary intervention
triple antithrombotic
oral anticoagulation
antiplatelet drug
作者简介
赵静,女,主管中药师,主要从事心血管疾病合理用药方面的研究,E-mail:dr_zhaojing@163.com。
