急性脑梗死患者动脉粥样硬化程度与C反应蛋白的相关性分析被引量：2

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摘要目的探究急性脑梗死患者动脉粥样硬化(atherosclerosis,AS)程度、斑块稳定性与血清C反应蛋白(C-reactive protein,CRP)浓度相关性。方法选取我院2017年1月至2017年12月收治的120例急性脑梗死患者作为研究对象。将所有患者按照脑梗死病灶大小分成腔隙性脑梗死组(46例)、小面积脑梗死组(42例)和大面积脑梗死组(32例)。所有患者经颈动脉彩超确诊颈动脉内膜厚度(IMT)增厚者82例,非IMT增厚者38例。按照颈动脉斑块状态将例IMY增厚者分成管壁增厚组(25例)、硬斑块组(20例)、混合性斑块组(19例)和软斑组(例)。采取免疫散射比浊法测量患者血清中的CRP浓度,对比、分析IMT增厚组与非IMT增厚组,稳定斑块组与不稳定斑块组,不同面积脑梗死组间CRP浓度。结果与非IMT增厚组相比,IMT增厚组CRP浓度更高;与稳定性斑块组相比,不稳定斑块组CRP浓度更高;CRP浓度随着脑梗死面积增加而升高,P<0.05,差异有统计学意义。结论CRP浓度与急性脑梗死患者动脉粥样硬化程度、斑块稳定性及患者病情密切相关。

作者徐莹

机构地区吉林省神经精神病医院神经内科

出处《中国医药指南》 2020年第4期69-70,共2页 Guide of China Medicine

关键词急性脑梗死动脉粥样硬化程度 C反应蛋白相关性

分类号 R743.33 [医药卫生—神经病学与精神病学]

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