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不同型别人乳头瘤病毒(HPV)与宫颈癌临床病理及预后的关系分析 被引量:6

Analysis of the relationship between different types of human papillomavirus(HPV) and the clinicopathology and prognosis of cervical cancer
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摘要 目的分析不同型别人乳头瘤病毒(HPV)与宫颈癌临床病理以及预后的关系。方法选择本院2017年12月至2018年12月收治的宫颈癌患者、宫颈癌前病变患者作为研究对象,分别抽选出120例患者参与研究。所有患者均接受HPV检测,比较不同型别HPV感染情况、治疗前后高危HPV感染率。结果宫颈癌患者HPV感染率高于宫颈癌前病变患者,差异具有统计学意义(P<0.05)。宫颈癌患者高危型HPV感染率明显高于低危型HPV感染率,且与宫颈癌前病变患者相比,差异具有统计学意义(P<0.05)。治疗后,所有患者高危型HPV感染率均降低,治疗前后高危型HPV感染率比较差异具有统计学意义(P<0.05)。结论高危型HPV感染与宫颈癌的发生关系密切,应加强宫颈癌患者早期筛查与诊断,改善宫颈癌患者预后效果。 Objective To analyze the relationship between different types of human papillomavirus(HPV)and the clinicopathology and progno sis of cervical cancer.Methods From December 2017 to December 2018,120 patients with cervical cancer and cervical precancerous lesions were selected to participate in the study.All patients were tested for HPV.The infection rate of different types of HPV and high risk HPV before and after treatment were compared.Results The infection rate of HPV in patients with cervical cancer was higher than that in patients with cervical precancer ous lesions,the difference was statistically significant(P<0.05).The infection rate of high-risk HPV in patients with cervical cancer was significant ly higher than that of low-risk HPV,and the difference was statistically significant(P<0.05).After the treatment,the infection rate of high-risk HPV in all patients decreased,and there was significant difference between the two groups(P<0.05).Conclusion High risk HPV infection is closely re lated to the occurrence of cervical cancer.Early screening and diagnosis should be strengthened to improve the prognosis of cervical cancer.
作者 梁英 Liang Ying(Department of Gynecology,Anshan Hospital,the First Affiliated Hospital of China Medical University,Anshan,Liaoning,114000,China)
出处 《当代医学》 2020年第7期57-59,共3页 Contemporary Medicine
关键词 不同型别人乳头瘤病毒 宫颈癌 临床病理 预后 Different types of human papillomavirus Cervical cancer Clinicopathology Prognosis
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