摘要
报告雷珠单抗联合康柏西普玻璃体腔注射治疗难治性年龄相关性黄斑变性(age-related macular degeneration,AMD)1例,患者经15次抗血管内皮生长因子(vascular endothelial growth factor,VEGF)治疗55个月后,视力从0.25提高维持至1.0,黄斑光学相干断层扫描成像(optical coherence tomography,OCT)提示病灶逐渐缩小并趋于稳定。抗VEGF是治疗AMD的首选有效方法,其个性化治疗非常重要,在治疗过程中还需考虑药物的延迟应答,且OCT在观察AMD的病情变化中具有良好的应用价值。
This paper reports 1 case of refractory age-related macular degeneration(AMD)treated with combined intravitreal injections of lucentis and conbercept 15 times.After 15 combined injections of lucentis and conbercept,the patient got a gradually increased best corrected visual acuity(BCVA)and a diminishing maculopathy on optical coherence tomography(OCT),both keeping stable at the end of visit.It reveals that intravitreal lucentis combined with conbercept appeared to be an effective treatment for refractory AMD.The management of AMD should be individualized or personalized according diagnosis time and delayed response of drugs.OCT has a good application value in observing the changes of macular anatomical changes in AMD.
作者
彭立
陈敏华
谢青
PENG Li;CHEN Minhua;XIE Qing(Department of Ophthalmology,Haikou People’s Hospital,Haikou Hospital Affiliated to Xiangya Medical College,Central South University,Haikou 570000;Department of Ophthalmology,Second Xiangya Hospital,Central South University,Changsha 410011,China)
出处
《临床与病理杂志》
2019年第12期2855-2859,共5页
Journal of Clinical and Pathological Research
作者简介
通信作者:谢青,Email:doc_xq@163.com。
