摘要
目的分析老年男性心血管疾病患者发生阻塞性睡眠呼吸暂停的危险因素。方法选取福建医科大学附属协和医院呼吸科2017-01至2018-01收治的50例老年男性心血管疾病发生阻塞性睡眠呼吸暂停的患者作为观察组,同期选择50例未发生阻塞性睡眠呼吸暂停的老年男性心血管疾病患者作为对照组。收集患者的基础指标,采用Logistic回归分析影响老年男性心血管疾病患者发生阻塞性睡眠呼吸暂停的危险因素。结果观察组体质指数、臀围、颈围、腰围、血糖、胆固醇、纤维蛋白原、C反应蛋白及肿瘤坏死因子-α水平均明显高于对照组,差异均有统计学意义(P<0.05);两组舒张压、收缩压、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、甘油三酯比较,差异无统计学意义(P>0.05);Logistic回归分析结果显示,体质指数、颈围、血糖、胆固醇及C反应蛋白是老年男性心血管疾病患者发生阻塞性睡眠呼吸暂停的危险因素(P<0.05)。结论体质指数、颈围、血糖、胆固醇及C反应蛋白是老年男性心血管疾病患者发生阻塞性睡眠呼吸暂停的独立危险因素。
Objective To analyze the risk factors of obstructive sleep apnea in elderly male patients with cardiovascular disease,and to provide reference for clinical diagnosis and treatment.Methods 50 elderly male patients with obstructive sleep apnea caused by cardiovascular diseases treated in the department of respiration of Union Hospital Affiliated to Fujian Medical University from January 2017 to January 2018 were selected as the observation group and 50 elderly male patients without obstructive sleep apnea as the control group.The body mass index,neck circumference,waist circumference,hip circumference,blood pressure,blood lipid,fasting blood glucose,blood lipid,fibrinogen,C-reactive protein and tumor necrosis factor-αlevels of all subjects were measured and analyzed.Results The body mass index,hip circumference,neck circumference and waist circumference of the patients in the observation group were significantly higher than those in the control group,the difference was statistically significant(P<0.05);there was no statistically significant difference in diastolic and systolic blood pressure between the two groups(P>0.05).The levels of blood glucose,cholesterol,fibrinogen,C-reactive protein and TNF-αin the observation group were significantly higher than those in the control group(P<0.05).The patients were followed up for one year,and it was found that incidence of obstructive sleep apnea was positively correlated with body mass index,neck circumference,blood glucose,cholesterol and C-reactive protein(P<0.05),but not with other indexes(P>0.05).Conclusions Dyslipidemia,body mass index,neck circumference,systolic blood pressure and mean arterial pressure are independent risk factors for the onset of obstructive sleep apnea in elderly men,and can also increase the risk of cardiovascular disease and chronic obstructive sleep apnea.
作者
谭雪雪
TAN Xuexue(Department of Respiration of Union Hospital Affiliated to Fujian Medical University,Fuzhou 350000,China)
出处
《中华灾害救援医学》
2019年第12期682-684,687,共4页
Chinese Journal of Disaster Medicine
作者简介
通信作者:谭雪雪,E-mail:double_snow@126.com。
