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抗生素联合序贯清金化痰汤治疗重症肺炎临床研究 被引量:9

Clinical Study on Antibiotics Combined with Sequential Qingjin Huatan Decoction in the Treatment of Severe Pneumonia
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摘要 目的研究分析在重症肺炎(SP)患者中采取序贯清金化痰汤联合抗生素治疗的效果。方法将2018年1月-2018年8月在赣州市第三人民医院接受治疗的重症肺炎(SP)患者86例设为研究对象,经电脑随机法分为观察组(43例)和对照组(43例)。对照组中患者均采用抗生素治疗,观察组中患者采用序贯清金化痰汤以及抗生素联合治疗。对比2组患者的炎性因子、肺功能以及生活质量情况。结果治疗后2组患者的IL-2、IL-6、CRP均显著低于治疗前(P<0.05),治疗后观察组患者的IL-2、IL-6、CRP均显著低于对照组(P<0.05),治疗后2组患者的FEV1、FVC、PEF均显著高于治疗前(P<0.05),治疗后观察组患者的FEV1、FVC、PEF均显著高于对照组(P<0.05)。治疗后2组患者的BI分数以及Rankin分数显著高于治疗前(P<0.05),治疗后观察组中患者的BI分数以及Rankin分数显著高于对照组(P<0.05)。结论临床上在治疗重症肺炎患者时,相较于单一的抗生素治疗,采用抗生素联合序贯清金化痰汤治疗效果更佳,具有较高的临床推广价值。 Objective To study and analyze the effect of sequential Qingjin Huatan decoction and combination of antibiotics in patients with severe pneumonia(SP).Methods 86 cases of SP patients treated in our hospital from January 2018 to August 2018 were selected as study subjects,and were randomly divided into observation group(43 cases)and control group(43 cases)by computer.Patients in the control group were treated with antibiotics,while patients in the observation group were treated with sequential qingjinhuatan decoction and combined antibiotics.Inflammatory factors,lung function and quality of life were compared between the two groups.Results AFTer treatment,IL-2,IL-6 and CRP of the two groups were significantly lower than before treatment(P<0.05).After treatment,IL-2,IL-6 and CRP of the observation group were significantly lower than those of the control group(P<0.05).After treatment,FEV1 and FVC,PEF of the two groups were significantly higher than those before treatment(P<0.05).After treatment,FEV1 and FVC,PEF of the observation group were significantly higher than that of control group(P<0.05).The BI and Rankin scores of the patients in the two groups after treatment were significantly higher than those before treatment(P<0.05),and the BI and Rankin scores of the patients in the observation group after treatment were significantly higher than those in the control group(P<0.05).Conclusion In the clinical treatment of severe pneumonia patients,compared with the single antibiotic treatment,the use of antibiotics combined with sequential Qingjin Huatan decoction has better therapeutic effect and higher promotion value.
作者 章东元 王桂妹 ZHANG Dongyuan;WANG Guimei(Department of Gerontology,Ganzhou Third People's Hospital,Jiangxi Province,Ganzhou 341000,China)
出处 《中国中医药现代远程教育》 2019年第23期78-79,共2页 Chinese Medicine Modern Distance Education of China
关键词 重症肺炎 抗生素 清金化痰汤 序贯 肺功能 炎性因子 咳嗽 severe pneumonia antibiotics Qingjin Huatan decoction sequential lung function inflammatory cytokines cough
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