摘要
目的探讨肠内营养联合微生态免疫营养在老年症状性颈动脉狭窄支架成形术围手术期的应用效果。方法将我院2016年5月-2019年2月收治的94例老年急性脑梗死并梗死侧颈动脉狭窄≥50%患者随机分为对照组与研究组。对照组围手术期给予肠内营养支持,研究组给予肠内营养联合微生态免疫营养支持。检测两组治疗前、后血清白蛋白(ALB)、总蛋白(TP)、前白蛋白(PA)、免疫相关指标(CD3^+、CD4^+、CD8^+、CD4^+/CD8^+)、美国国立卫生研究院脑卒中量表(NIHSS)评分及观察术后并发症。结果研究组治疗后血清ALB、TP、PA及CD3^+、CD4^+、CD4^+/CD8^+与治疗前比较均无明显差异(均P>0.05),对照组治疗后各血清指标均低于治疗前及研究组(均P<0.05);研究组治疗后NIHSS评分低于治疗前及对照组(均P<0.05);研究组总并发症发生率低于对照组(P<0.05)。结论对行颈动脉狭窄支架成形术治疗的老年急性脑梗死患者围手术期给予肠内营养联合微生态免疫营养,可满足机体营养需求,维持免疫功能,并可促进神经功能改善,减少并发症发生。
Objective To explore the effect of enteral nutrition combined with microecological immune nutrition during the perioperative period of stenting for senile symptomatic carotid artery stenosis.Methods Ninety-four elderly patients with acute cerebral infarction complicated by carotid artery stenosis of infarcted side≥50%were randomly divided into control group or observation group.The control group received enteral nutrition alone during perioperative period,while the observation group received enteral nutrition combined with microecological immune nutrition.The serum albumin(ALB),total protein(TP),prealbumin(PA),immune related indicators(CD3^+,CD4^+,CD8^+,CD4^+/CD8^+),the National Institutes of Health Stroke Scale(NIHSS)scores and the postoperative complications before and after treatment were compared between the groups.Results There were no significant changes in the levels of serum ALB,TP,PA,CD3^+,CD4^+and CD4^+/CD8^+in the observation group after treatment(all P>0.05),but in the control group,which reduced after treatment and were lower than those in the observation group,with significant differences(all P<0.05).The NIHSS score of the observation group was lower after treatment and lower than those of the control group,with significant differences(all P<0.05).The incidence rate of total complications in the observation group was lower than that in the control group,with significant difference(P<0.05).Conclusion Enteral nutrition combined with microecological immune nutrition during perioperative period for elderly patients with acute cerebral infarction undergoing carotid artery stenting can meet the nutritional needs of the body,maintain immune function,help to improve nerve function and reduce the occurrence of complications.
作者
陈艳
郑峥
程琼
李永坤
林帆
吕心阳
CHEN Yan;ZHENG Zheng;CHENG Qiong;LI Yongkun;LIN Fan;LYU Xinyang(Geriatrics Department,Provincial Clinical Medical College of Fujian Medical University,Fujian Provincial Hospital,Fuzhou,Fujian 350000,China)
出处
《中国微生态学杂志》
CAS
CSCD
2019年第11期1297-1303,共7页
Chinese Journal of Microecology
关键词
肠内营养
微生态免疫营养
急性脑梗死
颈动脉支架成形术
Enteral nutrition
Microecological immune nutrition
Acute cerebral infarction
Carotid artery stenting
作者简介
通信作者:陈艳(1977-),女,研究生,从事老年学科研究,E-mail:cy514zz@163.com。
