摘要
光动力疗法(PDT)是近年来皮肤性病学领域一项新的有效治疗手段。PDT已经逐渐应用于多种皮肤病的治疗,其中包括尖锐湿疣、重度痤疮、脂溢性角化、银屑病、扁平苔藓、硬化萎缩性苔藓、寻常疣、皮肤癌和癌前病变等,并获得了较佳的治疗效果。无论是单独应用还是与激光、药物联合应用,患者耐受性和疗效都已经得到国内外学者的广泛肯定。然而,PDT产生的疼痛感使得此疗法在临床应用有一定的局限性,如何缓解和控制PDT中产生的疼痛感是目前亟待解决的问题,文中就PDT治疗产生疼痛的原理及疼痛的治疗进展进行综述。
In recent years,photodynamic therapy(PDT)has been a new and effective treatment in dermatology and venereology,including several clinical skin diseases such as condyloma acuminata,severe acne,seborrheic keratosis,psoriasis,lichen planus,sclerosing atrophic lichen,verruca vulgaris,skin cancer and precancerous lesions.Regardless of whether applied alone or combined with laser and medicine,PDT has been approved both in China and abroad due to high efficacy and good tolerance.However,the pain during and after the PDT had this technology restricted in the clinic.How to relieve and control the pain caused by the PDT treatment needs to be addressed.In the paper,the principle of PDT-associated pain and the recent advances in pain management during PDT have been summarized.
作者
靳峰阳
石卫东
JIN Fengyang;SHI Weidong(Wuhan Institute for the Prevention and Treatment of Dermatology,Wuhan 430031,China)
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2019年第12期1429-1432,共4页
The Chinese Journal of Dermatovenereology
关键词
光动力治疗
疼痛
Photodynamic therapy
Pain