摘要
目的探讨单耐异烟肼肺结核患者实施不同治疗方案治疗的临床效果。方法纳入2017年2月—2018年2月本院收治的单耐异烟肼肺结核患者100例进行研究,以挂号就诊单病案号单、双数为基准,分为研究组(50例)、对照组(50例),研究组:莫西沙星+乙胺丁醇+利福喷丁治疗,对照组:左氧氟沙星+乙胺丁醇+利福喷丁治疗,对比两组不良反应发生率、痰菌转阴率。结果不良反应发生率对比:研究组低于对照组;痰菌转阴率对比:研究组高于对照组,P<0.05,差异有统计学意义。结论单耐异烟肼肺结核患者实施莫西沙星+乙胺丁醇+利福喷丁治疗的临床效果显著,可提高痰菌转阴率。
Objective To investigate the clinical effects of different treatment regimens for patients with single-resistant isoniazid tuberculosis.Methods One hundred patients with single-resistant isoniazid tuberculosis admitted to the hospital from February 2017 to February 2018 were enrolled in the study.They were divided into the study group and the control group based on the registration cardnumber of single and double,with 50 cases in each group.The study group was given moxifloxacin,ethambutol and rifapentine for treatment,the control group was given levofloxacin,ethambutol and rifapentine for treatment,compare the incidence of adverse reactions,the rate of sputum negative conversion.Results The incidence of adverse reactions was compared:the study group was lower than the control group;the comparison of sputum negative conversion rate:the study group was higher than the control group,P<0.05,the difference was statistically significant.Conclusion The clinical effect of moxifloxacin+ethambutol+rifapentine in patients with single-resistant isoniazid tuberculosis is significant,which can improve the rate of sputum negative conversion.
作者
宋利芬
SONG Lifen(Department of Pharmacy,Inner Mongolia Autonomous Region Fourth Hospital,Hohhot Inner Mongolia 010010,China)
出处
《中国继续医学教育》
2019年第27期141-142,共2页
China Continuing Medical Education
关键词
异烟肼
利福平
单耐
肺结核
痰菌转阴率
isoniazid
rifampicin
single resistance
isoniazid
tuberculosis
the rate of sputum negative conversion
