摘要
目的:分析左氧氟沙星在治疗耐多药肺结核病中的治疗疗效。方法:选取2014年2月至2014年9月在吉安市疾病预防控制中心确诊的60例耐多药肺结核病患者,将所有患者随机分为两组,各30例,对照组采用3SEL2DZ/15EL2D治疗方案,观察组则采用3Cm VL2DZ/15VL2D方案治疗,分析比较两组治疗疗效。结果:观察组患者痰菌转阴率显著高于对照组,差异显著(P<0.05);两组不良反应率对比,无显著差异(P>0.05);观察组患者治疗有效率明显高于对照组,差异显著(P<0.05);观察组患者病灶吸收情况优于对照组,差异显著(P<0.05)。结论:采用左氧氟沙星治疗耐多药肺结核病安全性高、不良反应少、治疗有效率高,在临床应用中值得推广。
Objective：To analyze the treatment effect of multidrug resistance tuberculosis by levofloxacin.Methods：60 cases of patients with multidrug resistance tuberculosis at the Centers for Disease Control and Prevention of Ji’an City from February 2014 to September 2014 randomly divided into two groups,30 cases in each.The control group used the therapeutic schedule of 3SEL2DZ/15EL2 D,the treatment group used the therapeutic schedule of 3Cm VL2DZ/15VL2 D,and then the treatment effect was compared.Results：The sputum negative conversion rate of the treatment group was significantly higher than the control（P〈0.05）.The adverse reaction rate of two groups showed no statistical significance（P〉0.05）.The lesions absorption situation of the treatment group was better than the control group（P〈0.05）.Conclusion：Treatment effect of multidrug resistance tuberculosis by levofloxacin showed high safety,fewer adverse reactions,thus it is worth promotion in the clinical application.
作者
郭江凌
GUO Jiang-ling(The Centers for Disease Control and Prevention of Ji＇an City, Ji＇an Jiangxi 343000, Chin)
出处
《药品评价》
CAS
2016年第23期31-32,48,共3页
Drug Evaluation
关键词
左氧氟沙星
耐多药肺结核病
疗效
Levofloxacin
Multidrug Resistance Tuberculosis
Treatment Effect
作者简介
郭江凌，女，学士学位，主管药师。研究方向：临床药学。电话：0796-8222666；E-mail：gjljacdcb@163．com
