摘要
咪唑类化合物具有广谱生物活性,在农药、医药、化工、材料等领域应用广泛.设计合成了25种1,3-咪唑啉类化合物,产物结构经1H NMR、13C NMR和IR确证,同时测定了目标化合物的杀菌活性.结果表明,在测试浓度下,大部分呈现中等至良好的活性,其中化合物D-24对油菜菌核病菌的抑制率为83.1%.
Imidazole derivatives have broad biological activity, and found wide application in fields of pesticide medicine, chemical industry and materials. A simple and efficient method to synthesize 1,3 -imidazolidines was described in this paper. The fungicidal activity of the obtained compounds was investigated. The results indicated that most of the compounds showed moderate to good activity at the test concentration. Compound D-24 showed 83.1% activity against S. sclerotiorum.
作者
马彩霞
焦银春
姚园
唐子龙
MA Cai-xia;JIAO Yin-chun;YAO Yucui;TANG Zi-long(Key Laboratory of Theoretical Organic Chemistry and Functional Molecule of Ministry of Education, Hunan University of Science and Technology, Xiangtan 411201,China;School of Chemistry and Chemical Engineering,Hunan University of Science and Technology, Xiangtan 411201,China)
出处
《精细化工中间体》
CAS
2019年第4期10-16,共7页
Fine Chemical Intermediates
基金
国家自然科学基金(21877034)
湖南省教育厅项目(17A066)
理论有机化学与功能分子教育部重点实验室开放基金(LKF1603)
关键词
1
3-咪唑啉
合成
杀菌活性
1,3-imidazolidine
synthesis
fungicidal activity
作者简介
马彩霞(1992-),女,山西吕梁人,硕士,研究方向:有机合成(E-mail:2948347605@qq.com);联系人:唐子龙,教授.研究方向:有机合成,药物合成。
