摘要
牛黄是牛科动物牛的干燥胆结石,是一种常用的名贵中药,疗效显著,使用广泛,有体外培育牛黄、人工牛黄和培植牛黄3 种代用品。《中国药典》2015年版一部共收载含牛黄及代用品制剂8 9 个品种,笔者对相关品种项下牛黄及代用品的标准情况进行了汇总,旨在为含牛黄中成药中牛黄的标准提高提供建议和参考;并结合近些年含牛黄中成药的质量研究情况,对制剂中牛黄及代用品相关的质量问题进行汇总,为有关部门监管政策的制定和标准修订提供参考。
Calculus Bovis is the dry gall-stone of Bos taurus domesticus Gmelin, which is the most precious traditional Chinese med icine for its incomparable therapeutic effects. In vitro cultured Calculus Bovis, cultured Calculus Bovis and artificial Calculus Bovis are developed as the substitutes of Calculus Bovis. The Chinese Pharmacopoeia 2015 edition includes 89 Chinese patent drugs containing cow-bezoar and its substitutes. In this paper, the standards of Calculus Bovis and its substitutes in 89 Chinese patent drugs were re viewed to provide suggestions and reference for improving the relative standards. The qualities of Calculus Bovis and its substitutes of several Chinese patent drugs were summarized and analyzed based on the quality research of these drugs in recent years to offer sugges- tions for the revision of quality standards of relevant drugs and regulatory policy.
出处
《中国药学杂志》
CAS
CSCD
北大核心
2019年第17期1374-1379,共6页
Chinese Pharmaceutical Journal
关键词
牛黄
体外培育牛黄
人工牛黄
质量情况
中成药
Calculus Bovis
in vitro-cultured Calculus Bovis
artificial Calculus Bovis
quality status
Chinese patent drug
作者简介
胡晓茹,女,博士,副研究员研究方向:中药质量控制研究;通讯作者:戴忠,男,博士,研究员,硕士生导师,研究方向:中药质量控制及中药化学对照品研究,Tel:(010)67095150,E-mail:daizhong@nifdc.org.cn;马双成,男,博士,研究员,博士生导师,研究方向:药物分析及中药学,Tel:(010)67095272,E-mail:masc@nifdc.org.cn.
