摘要
目的研究目标导向性液体治疗对凶险性前置胎盘患者围术期容量及凝血功能的影响。方法选取2015年1月至2018年1月于医院接受治疗凶险性前置胎盘剖宫产术患者98例,依据治疗方案的不同分为常规补液组和目标管理补液组。分别记录两组患者术中不同时期血流动力学、凝血指标及血液乳酸含量及患者术后情况比较。结果相比常规补液组,目标管理补液组术中各时间点心静脉压(CVP)、平均血压(MBP)及纤维蛋白原(Fbg)值、尿显著量增加,且差异有统计学意义(P<0.05);术中出血量、悬浮红细胞输入量、血浆输入量、低血压出现次数、注射去氧肾上腺素量及心博量(△SV)显著减少且差异有统计学意义(P<0.05)。结论目标导向性液体治疗可以使患者围术期血流更稳定、凝血功能增强,并且改善预后。
Objective To study the effects of goal-directed fluid therapy on perioperative volume and coagulation function in patients with pernicious placenta previa.Methods 98 patients who were treated with cesarean section for pernicious placenta previa in the hospital from January 2015 to January 2018 were selected and divided into conventional fluid infusion group and goal management fluid infusion group according to the treatment regimens.Hemodynamics,coagulation parameters and blood lactic acid content at different time periods during operation and postoperative situation were compared between the two groups.Results Compared with conventional fluid infusion group,the central venous pressure(CVP),mean blood pressure(MBP),fibrinogen(Fbg)and urine were increased at each time point during operation in goal management fluid infusion group(P<0.05).The intraoperative blood loss,suspended red blood cell input,plasma input,hypotension frequency,injection of phenylephrine and stroke volume(△SV)were significantly reduced(P<0.05).Conclusion Goal-directed fluid therapy can make patients with more stable perioperative blood flow,enhance coagulation function,and improve prognosis.
作者
左国会
陶承燕
ZUO Guo-hui;TAO Cheng-yan(Department of obstetrics and postpartum rehabilitation, qianjiang district central hospital chongqing qianjiang ,409000)
出处
《血栓与止血学》
2019年第3期428-431,共4页
Chinese Journal of Thrombosis and Hemostasis
关键词
凶险性前置胎盘
目标导向性液体
凝血功能
围术期
Pernicious placenta previa
Goal-directed fluid
Coagulation function
Perioperative period
作者简介
通讯作者:陶承燕。
