摘要
鸡传染性法氏囊病(IBD)是由传染性法氏囊病病毒(IBDV)引起的急性、高度接触性传染病,主要感染3~6周龄雏鸡。自首次发现以来,它一直是家禽业经济损失的主要原因之一。IBDV具有分段的双链RNA基因组,易发生遗传变异,产生与现有商品化疫苗的抗原性不能完全匹配的流行毒株,从而导致免疫失败。因此迫切需要研发与临床流行毒株相匹配的新型疫苗用于IBD的防控。本文综述了该病毒当前流行病学和疫苗的研究进展,为IBD的防控提供参考。
Infectious bursal disease(IBD)is an acute,highly contagious infectious disease caused by infectious bursal disease virus(IBDV),which main infect 3 to 6 weeks old chicks. Since first been discoveried,it is one of the leading cause of financial loss in the poultry industry. IBDV has segmented double-stranded RNA genome,that prone to genetic variation to produce epidemic strains that do not fully match the antigenicity of existing commercial vaccines and leading to immune failure. Therefore,it is urgent to develop new vaccines that match the clinical epidemic strains for the prevention and control of IBD. This article reviews the current epidemiology of the virus and the research progress of vaccine,providing reference for prevention and control of IBD.
作者
朱思思
李永红
Zhu sisi;Li yong hong(Guangdong Winsun Bio-pharmaceutical Co.,Ltd.,Guangzhou 511356,China)
出处
《广东畜牧兽医科技》
2019年第3期9-13,共5页
Guangdong Journal of Animal and Veterinary Science
关键词
传染性法氏囊病
传染性法氏囊病毒
疫苗
Infectious bursal disease
Infectious bursal disease virus
vaccines
作者简介
朱思思(1987-),女,江西人,硕士研究生,从事动物疫苗研究。E-mail:zhusisi1987@sina.com;通讯作者:李永红(1966-),男,广东人,硕士研究生,兽医师,从事禽病防控项目研究。E-mail:lyh25f@163.com.
