摘要
目的探讨创伤性骨折应用医用硫酸钙的临床效果及对患者VAS评分、生活质量的影响。方法 2016年5月—2017年5月南京市中医院骨伤科收治60例医用硫酸钙进行治疗的创伤性骨折患者,男性34例,女性26例;年龄20～72岁,平均51.3岁。将患者分为应用Osteoset^RDBM颗粒状医用硫酸钙组35例(Osteoset^RDBM组)和MIIG^RX3注射型医用硫酸钙组25例(MIIG^RX3组),研究两组患者的VAS评分、Osteoset^RDBM及MIIG^RX3灰度变化等。结果两组患者治疗前VAS评分差异无统计学意义[(6.8±1.4)分vs.(7.2±1.3)分,P=0.061]。治疗后3、6、12个月VAS评分均有一定程度的改善,Osteoset^RDBM组分别为(2.6±1.3)、(1.2±1.6)、(1.1±1.2)分,MIIG^RX3组分别为(2.2±0.8)、(1.1±0.6)、(0.8±0.5)分,组间比较差异无统计学意义;两组患者治疗后8周未见医用硫酸钙明确显影,差异无统计学意义(P>0.05);两组灰度变化比较,1周与2、4、6、8周比较差异有统计学意义(P<0.05);治疗后两组患者生理功能(PF)、躯体疼痛(BP)、总体健康感(GH)、心理健康(MH)、社会功能(SF)、生命活力(VT)、生理问题导致的角色受限(RP)、情感问题导致的角色受限(RE)评分均出现上升,组间比较差异无统计学意义(P>0.05)。结论在对创伤性骨折患者进行治疗的过程中,使用人工骨医用硫酸钙效果良好,值得在临床上进一步推广和应用。
Objective To investigate the clinical effect of medical calcium sulfate on traumatic fracture and its influence on VAS score and quality of life. MethodsFrom May 2016 to May 2017,60 patients with traumatic fracture were treated with calcium sulfate in Department of Orthopedics and Traumatology,Nanjing Hospital of Traditional Chinese Medicine. There were 34 males and 26 females;the age ranged from 20 to 72 years,with an average of 51.3 years. The patients were divided into Osteoset RDBM group (35 cases) and MIIG RX3 group (25 cases).The VAS score,and gray level changes of Osteoset RDBM and MIIG RX3 were recorded and compared in the two groups. Results There was no significant difference in VAS score between the two groups before treatment (6.8±1.4 vs. 7.2±1.3, P =0.061). The VAS score was improved at 3,6,12 months after treatment (Osteoset RDBM group=2.6±1.3,1.2±1.6,1.1±1.2,respectively;MIIG RX3 group=2.2±0.8,1.1±0.6,0.8±0.5,respectively). There was no clear development of medical calcium sulfate in the two groups at 8 weeks after operation,and there was no significant difference between the two groups ( P >0.05). The scores of physiological function (PF),body pain (BP),general health (GH),mental health (MH),social function (SF),vitality (VT),role limitation caused by physiological problems (RP) and role limitation caused by emotional problems (RE) all increased,but there was no significant difference between the two groups ( P >0.05). ConclusionIn the treatment of traumatic fracture patients,medical calcium sulfate has good effect,which is worthy of further promotion and application in clinical practice.
作者
张琦
刘畅畅
ZHANG Qi;LIU Chang-chang(Department of Orthopedics and Traumatology, Nanjing Hospital of Traditional Chinese Medicine,Nanjing210000,China)
出处
《创伤外科杂志》
2019年第4期296-299,共4页
Journal of Traumatic Surgery
关键词
创伤性骨折
医用硫酸钙
降解速度
预后
traumatic fracture
medical calcium sulfate
degradation rate
prognosis
