摘要
弥散张量成像(diffusion tensor imaging,DTI)利用水分子弥散运动描述大脑空间结构,获得脑肿瘤的浸润破坏情况,使得疾病的诊断方式实现从宏观至微观、从形态学上升至形态与代谢并重,为脑肿瘤的诊疗研究带来新的机遇。在这篇综述中,概述了DTI技术的理论基础及目前的局限性,并对其在脑肿瘤放射治疗及其疗效预判中的应用价值进行全面讨论。DTI为脑肿瘤的放疗方案制定提供重要的影像学信息。
Diffusion tensor imaging (DTI) uses the diffusion motion of water molecules to describe the spatial structure of brain.DTI,which can obtain the infiltration of brain tumors into normal physiological structures,makes the diagnosis of diseases change from macroscopic to microscopic,from morphology to both morphology and metabolism,bringing new opportunities for the diagnosis and treatment of brain tumors.In this review,we outlined the theoretical basis and current technical limitations of DTI,and comprehensively discussed its research values in brain tumors radiotherapy treatment and its prognostic value.We believe that DTI can provide important imaging information for radiotherapy planning of brain tumors.
作者
吴凌云
严丹方
严森祥
Wu Lingyun;Yan Danfang;Yau Senxiang(Department of Radiation Oncology,the First Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou 310003,China)
出处
《中华放射医学与防护杂志》
CAS
CSCD
北大核心
2019年第3期236-240,共5页
Chinese Journal of Radiological Medicine and Protection
关键词
弥散张量成像
放射治疗
脑肿瘤
核磁共振
Diffusion tensor imaging
Radiotherapy
Brain tumor
Magnetic resonance imaging
作者简介
通信作者:严森祥,Email:yansenxiang@zju.edu.cn.
