术中放疗在早期乳腺癌保乳手术中的应用价值被引量：7

Clinical value of intraoperative radiotherapy combined with breast conserving surgery in early breast cancer

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摘要目的探讨术中放疗在早期乳腺癌保乳手术中的临床疗效及美容效果。方法回顾性分析郑州大学第一附属医院2013年10月至2015年8月65例行保乳手术的早期乳腺癌患者的临床资料。根据治疗方法将患者分为术中放疗组(34例,行保乳术及术中放疗)及术后放疗组(31例,行保乳术及术后全乳及瘤床加量外照射)。随访观察比较两组患者切口并发症发生情况、局部复发情况及乳房美容效果。结果随访发现术中放疗组术后切口并发症发生率(5.9%)高于术后放疗组(3.2%),但差异未见统计学意义(P>0.05);术中放疗组乳房美容效果优于术后放疗组,差异有统计学意义(P<0.05)。两组均未出现局部复发及远处转移。结论术中放疗的近期疗效尚可,不良反应少,临床安全性高,美容效果好,有临床应用价值。 Objective To investigate the clinical value of intraoperative radiotherapy (IORT) combined with breast conserving surgery (BCS) in early breast cancer. Methods The clinical data of 65 patients with early-stage breast cancer treated by BCS and IORT in the First Affiliated Hospital from October 2013 to August 2015 were retrospectively analyzed. And enrolled patients were divided into IORT group (34 patients, underwent BCS and IORT) and postoperative radiotherapy group (31 patients, underwent postoperative external beam radiotherapy). Incidence of local complications, recurrence condition, the cosmetic results of the two groups were observed and compared. Results The incidence of local complications in IORT group (5.9%) was higher than that in postoperative radiotherapy group (3.2%), but the difference was not statistically significant (P>0.05). The cosmetic result in IORT group was better than that in postoperative radiotherapy group (P<0.05). No one of the two groups had local recurrence or distant metastasis. Conclusions IORT has great short-term curative effect for patients with early breast cancer. And it is safe and reliable with less adverse reactions and better cosmetic outcomes, which has clinical application value.

作者朱敏敏赵兵高远李国文 Zhu Minmin;Zhao Bing;Gao Yuan;Li Guotven(Department of Radiotherapy,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区郑州大学第一附属医院放疗科

出处《中国实用医刊》 2019年第1期26-28,共3页 Chinese Journal of Practical Medicine

关键词早期乳腺癌保乳术术中放疗 Early-stage breast cancer Breast-conserving surgery Intraoperative radiotherapy

分类号 R737.9 [医药卫生—肿瘤]

作者简介通信作者:李国文,Email:lgw0371@163.com.

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参考文献2

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2刘军,黄林平,周伟,熊英,戴甜甜,韩媛媛.术中放疗在早期乳腺癌保乳手术中的应用观察[J].中日友好医院学报,2016,30(3):137-140. 被引量：7

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