期刊文献+

多囊卵巢综合征患者胰岛素抵抗的研究进展 被引量:50

Research progress in insulin resistance in patients with polycystic ovary syndrome
在线阅读 下载PDF
导出
摘要 多囊卵巢综合征(PCOS)是一种常见的影响生育功能的妇科内分泌疾病,被认为与遗传、代谢、内分泌及环境等多因素相关。PCOS患者的胰岛素抵抗增加了2型糖尿病、高血压、脂质代谢异常等发生的风险,越来越多的研究开始关注PCOS患者的胰岛素抵抗,本文从胰岛素抵抗的发生机制、评估、治疗等方面阐述其在PCOS中的研究进展。 Polycystic ovary syndrome(PCOS) is a common gynecological endocrine disease affecting fertility. It is considered to be related to many factors such as heredity,metabolism,endocrine and environment. Insulin resistance increases the risk of developing type 2 diabetes,hypertension and abnormal lipid metabolism in patients with PCOS. More studies have paid attention to insulin resistance in patients with PCOS. This article expounds the latest research progress in the pathogenesis,evaluation and treatment of insulin resistance in the patients with PCOS.
作者 丁风娟 郝翠芳 DING Feng-juan;HAO Cui-fang(Binzhou Medical University,Yantai 264033;Center for Reproductive Medicine,Yantai Yuhuangding Hospital Affiliated to Qingdao University,Yantai 264000)
出处 《生殖医学杂志》 CAS 2019年第3期315-319,共5页 Journal of Reproductive Medicine
关键词 多囊卵巢综合征 胰岛素抵抗 高胰岛素血症 Polycystic ovarian syndrome Insulin resistance Hyper-insulinemia
作者简介 丁风娟,女,山东聊城人,硕士研究生,妇产科学(生殖医学)专业;通讯作者:郝翠芳,Email:cuifang-hao@163.com.
  • 相关文献

参考文献2

二级参考文献19

  • 1Dunaif A. Hyperandrogenic anovulation (PCOS): a unique disorder of insulin action associated with an increased risk of non-insulin-dependent diabetes mellitus [J]. Am J Med,1995, 98(1): 33-39.
  • 2Dunaif A. Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis [J].Endocr Rev, 1997, 18(6): 774-800.
  • 3Ben-shlomo I. The polycystic ovary syndrome: what does insulin resistance have to do with it[J]? Reprod Biomed Online, 2003,6 (1): 36-42.
  • 4Mitwally MF, Kuscu NK, Yalcinkays TM. High ovulatory rates with use of troglitazone in clomiphene-resistant women with polycystic ovary syndrome [J]. Hum Reprod, 1999, 14(11) :2700-2703.
  • 5Loi CM, Alvey CM, Vassos AB, et al. Steady-state pharmacokinetics and dose proportionality of troglitazone and its metabolites [J]. J Clin Pharmacol, 1999, 39(9): 920-926.
  • 6Ke WX, Shah GQ, Hua SY. Different responses of insulin,C-peptide, and testosterone to an oral glucose tolerance test in two groups of women with polycystic ovarian syndrome [J]. Acta Obstet Gynecol Scand, 1996, 75(2): 166-169.
  • 7Franks S. Assessment and management of anovulatory infertility in polycystic ovary syndrome [J]. Endocrinol Metab Clin North Am, 2003, 32(3): 639-651.
  • 8Szilagyi A, Szabo I. Endocrine characteristics of polycystic ovary syndrome (PCOS)[J]. Indian J Exp Biol, 2003, 41(7): 694-700.
  • 9Weerakiet S, Srisombut C, Bunnag P, et al. Prevalence of type 2 diabetes mellitus and impaired glucose tolerance in Asian women with polycystic ovary syndrome [J]. Int J Gynaecol Obstet,2001,75(2) :177-184.
  • 10Ciampelli M, Fulghesu AM, Cucinelli F, et al. Heterogeneity in beta cell activity, hepatic insulin clearance and peripheral insulin sensitivity in women with polycystic ovary syndrome[J]. Hum Reprod, 1997,12(9): 1897-1901.

共引文献27

同被引文献611

引证文献50

二级引证文献338

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部