摘要
系统性红斑狼疮是一种病因不明的自身免疫性疾病,其特点是产生一系列针对核抗原和细胞质抗原的自身抗体。自身抗体是一种针对自身组织、器官、细胞和细胞成分的抗体,在正常人体血液中可有较低水平的自身抗体,超过一定水平的自身抗体会对身体产生损害,从而引起疾病。自身抗体可见于系统性红斑狼疮、系统性硬化症等多种自身免疫性疾病,研究自身抗体与相应疾病的关系可提高疾病确诊率,降低误诊率及漏诊率,有利于疾病治疗及预后。
Systemic lupus erythematosus is a typical chronic autoimmune disease involving multiple systemic and organ damages,which is characterized by product of a large number of autoantibodies of the nuclear antigens and cytoplasmic antigens.Autoantibody is a kind of antibody mainly against own tissue,organ,cell and cellular components.There is a low degree of autoantibodies in the blood of normal humans,excessive levels of autoantibodies can damage the body and cause diseases.Autoantibody can be found in various autoimmune diseases such as systemic lupus erythematosus and systemic sclerosis.Studying the relationship between autoantibodies and the corresponding diseases can improve the diagnosis of the condition,reduce misdiagnosis and missed diagnosis rate,which is conductive to the treatment and prognosis.
作者
黎毅
潘邦贫
李晓岚
LI Yi;PAN Bangpin;LI Xiaolan(Department of Dermatology,the Second Affiliated Hospital of Kunming Medical University,Kunming 650504,China)
出处
《医学综述》
2019年第1期34-39,共6页
Medical Recapitulate
关键词
系统性红斑狼疮
自身抗体
抗核抗体谱
抗心磷脂抗体
Systemic lupus erythematosus
Autoantibodies
Antinuclear antibody spectrum
Anticardiolipin antibody
作者简介
通信作者:李晓岚E-mail:lixiaolan96@hotmail.com
