摘要
门静脉高压症作为一种常见的临床综合征,其引发严重的并发症如慢性肝病患者的食管胃静脉曲张、腹水和肝性脑病等,会间接影响肝硬化患者的预后情况。目前,肝静脉压力梯度(HVPG)为评估门静脉高压症的金标准,但因有创、价格昂贵等特点限制了其在临床上的推广使用。因此,无创且精确的技术研发在疾病诊断、风险分层、疗效监测、预后预测等方面都至关重要。阐述了临床实践中门静脉高压症无创性检测方法的最新进展,强调注重无创技术研发,HVPG检测标准化与疾病精准分层管理的重要性。
As a common clinical syndrome,portal hypertension can cause severe complications including gastroesophageal varices,ascites,and hepatic encephalopathy in patients with chronic liver diseases,which indirectly affects the prognosis of cirrhotic patients. At present,hepatic venous pressure gradient( HVPG) is the gold standard for the evaluation of portal hypertension,but its clinical application is limited by invasiveness and high cost. Therefore,the development of noninvasive and accurate measurements for portal pressure is crucial in the diagnosis,risk stratification,outcome monitoring,and prognosis prediction. This article reviews the latest advances in noninvasive examinations of portal hypertension in clinical practice and emphasizes the research and development of noninvasive techniques,HVPG standardization,and precise risk stratification management.
作者
林姗姗
刘燕娜
祁小龙
LIN Shanshan;LIU Yanna;QI Xiaolong(Chinese Portal Hypertension Diagnosis and Monitoring Study Group,Laboratory of Liver Hemodynamics,Hepatology Center,Nanfang Hospital,Guangzhou 510515,China)
出处
《临床肝胆病杂志》
CAS
北大核心
2019年第1期33-37,共5页
Journal of Clinical Hepatology
关键词
高血压
门静脉
血清学试验
超声检查
弹性成像技术
磁共振成像
hypertension,portal
serologic tests
ultrasonography
elasticity imaging techniques
magnetic resonance imaging
作者简介
林姗姗(1997-),女,主要从事门静脉高压诊断研究;通信作者:祁小龙,电子信箱:qixiaolong@vip.163.com。
