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阿司匹林联合氯吡格雷治疗脑梗塞的疗效分析 被引量:8

Analysis of Curative Effect of Aspirin Combined with Clopidogrel in Treatment of Cerebral Infraction
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摘要 目的探究采用阿司匹林联合氯吡格雷治疗脑梗塞的临床效果。方法选取2013年6月—2016年6月入院的100例确诊为脑梗塞的患者,将其随机分为对照组与研究组,对照组采用单一阿司匹林药物治疗,研究组患者采取阿司匹林联合氯吡格雷治疗,比较两组患者的治疗效果。结果两组患者在治疗前其NIHSS评分之间差异无统计学意义(P>0.05),治疗后,对照组NIHSS评分为(15.33±2.65)分,研究组NIHSS评分为(8.29±3.44)分,两组数据差异有统计学意义(t=6.800,P<0.05);对照组患者中治疗有效率为78.0%,研究组患者治疗有效率为96.0%,两组数据差异有统计学意义(χ~2=11.269,P<0.05)。结论利用阿司匹林联合氯吡格雷治疗患者脑梗塞效果明显,患者神经功能受损情况得到有效改善,具有临床应用价值。 Objective To study the clinical effect of aspirin combined with clopidogrel in treatment of cerebral infraction. Methods 100 cases of patients with cerebral infraction confirmed in our hospital from June 2013 to June 2016 were selected and randomly divided into two groups, the control group were treated with single aspirin, while the research group used the aspirin combined with clopidogrel for treatment, and the treatment effect was compared between the two groups. Results The differences in the NIHSS scores between the two groups before treatment were not obvious(P>0.05), after treatment, the NIHSS score in the control group and in the research group was respectively (15.33±2.65)points and (8.29±3.44)points, and the difference was obvious(t=6.800,P<0.05), and the treatment effective rate in the control group and in the research group was respectively 78.0% and 96.0%, and the difference was obvious(χ^2=11.269,P<0.05). Conclusion The application effect of aspirin combined with clopidogrel in treatment of cerebral infraction is obvious, and the nerve function injury condition of patients can be effectively improved, and it is of clinical application value.
作者 陈光友 CHEN Guang-you(Department of Neurology,Nanjing Yihe Rehabilitation Hospital,Nanjing,Jiangsu Province,210028 China)
出处 《系统医学》 2018年第22期61-62,71,共3页 Systems Medicine
关键词 脑梗塞 阿司匹林 氯吡格雷 联合用药 效果明显 应用价值 Cerebral infraction Aspirin Clopidogrel Combined medication Obvious effect Application value
作者简介 陈光友(1969-),男,江苏南京人,本科,主治医师,研究方向:神经内科方面。
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