摘要
布鲁氏菌病主要引起公犬的睾丸炎、附睾炎并造成不育.该文对一例患布病公犬各器官的组织进行了病理学以及抗原分布分析.结果表明,肝脏、脾脏、睾丸、淋巴结呈现广泛的炎性细胞浸润与实质细胞变性坏死,脾脏中观察到大量感染性肉芽肿.免疫组化结果表明,布鲁氏菌抗原主要分布于肝、脾、睾丸组织中的巨噬细胞和中性粒细胞胞浆中,与巨噬细胞的亲和力最强.
Brucellosis mainly causes orchitis,epididymitis and infertility in male dogs.In this study,the pathology and the antigen distribution of Brucella canis in organs were analyzed.The results showed that the liver,the spleen,the testis and the lymph nodes showed extensive inflammatory cell infiltration,degeneration and necrosis of parenchymal cells,and a large number of infectious granulomas were observed in the spleen.Results of immunohistochemistry showed that Brucella canis antigen was mainly distributed in the cytoplasm of macrophages and neutrophils in liver,spleen and testis and had the strongest affinity with macrophages.
作者
李平
涂蕊
朱子琦
刘新
肖启程
彭广能
钟志军
LI Ping;TU Rui;ZHU Zi-qi;LIU Xin;XIAO Qi-cheng;PENG Guang-neng;ZHONG Zhi-jun(Agricultural and Forestry Bureau of Qionglai, Qionglai 611530, Sichuan;Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine,Sichuan Agricultural University, Chengdu 611130, Sichuan;Agricultural Bureau of Suining, Suining 629000, Sichuan)
出处
《南京晓庄学院学报》
2018年第6期1-5,共5页
Journal of Nanjing Xiaozhuang University
基金
国家重点研发计划(2018YFD0500900)
国家自然科学基金项目(31000548)
成都大熊猫繁育研究基金会项目(CPF2015-4)
关键词
犬布鲁氏菌
组织病理学
免疫组化
Brucella canis
histopathology
immunohistochemistry
作者简介
李平,邛崃市农业和林业局兽医师,研究方向:动物卫生监督.E-mail:17782215@qq.com;通信作者:钟志军,博士,四川农业大学动物医学院教授,研究方向:动物疫病与人类健康.E-mail:zhongzhijun488@126.com
