摘要
目的:研究减肥中药专利文献的用药规律,为减肥中药的新药研发提供思路。方法:检索与减肥相关的中药复方专利,分析药味的出现次数,对出现频次高的药味进行分类,统计。结果:与肥胖有关中药专利文献中,出现频次较高的前十味药材依次为山楂、黄芪、白术、白芷、荷叶、泽泻、大黄、甘草、决明子、苍术,按照功效分类主要集中在补虚、清热、解表、消食、泻下功效的药味中。结论:肥胖与脾、胃、肝、肾等脏腑关系最为密切,多选用补虚、清热、解表、消食、泻下功效的药味,符合中医对肥胖疾病的病机认识,体现了治疗肥胖的中药复方组方特点。
Objective:To study the medication rule of obesity from the perspective of TCM patent literature,thus to provide ideas for new drug research of weight-loss.Methods:Patents of TCM compound formula related to weight-loss were reviewed to analyze the frequency of herb's application;on which basis,the top frequency herbs were classified for the statistics.Results:In the TCM literature related to obesity,the top ten herbs with higher application frequency were Shanzha(Hawthorn fruit),Huangqi(Milkvetch root),Baizhu(Atractylodes),Baizhi(Angelica),Heye(Lotus leaves),Zexie(Alisma),Dahuang(Rhubarb),Gancao(Licorice),Juemingzi(Cassia seed)and Cangzhu(Rhizoma atractylodis).The herbs were mainly distributed in the tonic drugs,antipyretic drugs,drugs to relieve exterior,digestive drugs,and purgative drugs according to their actions.Conclusion:Obesity is closely related to Spleen,Stomach,Liver,and Kidney;herbs with the action of tonifying,clearing heat,relieving exterior,helping digestion,or promoting purgation were often used;which comforms to the pathogenesis of obesity in TCM,and it embodies the characteristic of TCM compound formulas treating obesity.
作者
王永
王超
王世华
李向军
WANG Yong;WANG Chao;WANG Shihua;LI Xiangjun(Shijiazhuang Yiling Pharmaceutical Co., Ltd., Shijiazhuang 050035, China)
出处
《中医药学报》
CAS
2018年第6期83-88,共6页
Acta Chinese Medicine and Pharmacology
关键词
专利文献
肥胖
中药
山楂
荷叶
Patent literature
Obesity
Chinese medicinal
Hawthorn fruit
Lotus leaves
作者简介
王永(1980-),男,硕士,副主任药师,主要从事中药新药及知识产权工作;通讯作者:李向军(1975-),男,硕士,正高级工程师,硕士研究生导师,主要从事新药研发工作。
