摘要
目的:分析沙丁胺醇联合布地奈德治疗小儿哮喘急性发作的效果。方法:随机选取2016年5月-2017年5月本院儿科收治的哮喘急性发作患者60例作为研究对象,按照随机数x~表法将其分为观察组和对照组,各30例。对照组采纳沙丁胺醇治疗,观察组采纳沙丁胺醇联合布地奈德治疗,比较分析两组临床疗效、临床症状消失时间、不良反应及复发情况。结果:观察组总有效率为96.67%明显高于对照组的70.00%,差异有统计学意义(x^2=7.680 0,P=0.005 6)。观察组的哮鸣音、咳嗽、胸闷、气急症状消失时间均明显短于对照组,差异均有统计学意义(P<0.05)。观察组的不良反应发生率为6.67%,对照组为10.00%,两组不良反应发生情况比较,差异无统计学意义(x^2=0.218 2,P=0.640 4)。观察组的疾病复发率明显低于对照组,差异有统计学意义(x^2=4.043 1,P=0.044 4)。结论:沙丁胺醇联合布地奈德可有效减轻小儿哮喘急性发作患者病情,且不良反应较少,复发率较低,减轻患者痛苦,近、远期疗效显著,安全可行,临床上值得进一步推广。
Objective:To analyze the effect of Salbutamol combined with Budesonide in the treatment of children with acute asthma attack.Method:A total of 60 patients with acute asthma attack admitted in our hospital from May 2016 to May 2017 were randomly selected as the study objects.According to the random number table method,they were divided into observation group and control group,30 cases in each group.The control group was treated with Salbutamol treatment,the observation group was treated with Salbutamol combined with Budesonide treatment.The clinical efficacy,clinical symptoms disappeared time,adverse reactions and recurrence between the two groups were compared.Result:The total effective rate of the observation group was 96.67%,which was significantly higher than 70.00%of the control group,the difference was statistically significant(χ2=7.680 0,P=0.005 6).The disappearance time of wheezing,cough,chest tightness and shortness of breath in the observation group were significantly shorter than those in the control group,the differences were statistically significant(P<0.05).The incidence of adverse reactions was 6.67%in the observation group and 10.00%in the control group,there was no significant difference in the incidence of adverse reactions between the two groups(χ2=0.218 2,P=0.640 4).The recurrence rate of the observation group was significantly lower than the control group,the difference was statistically significant(χ2=4.043 1,P=0.044 4).Conclusion:Salbutamol combined with Budesonide can effectively alleviate the condition of children with acute asthma attack,the adverse reactions are less,the recurrence rate is lower,the pain of patients is alleviated,the short-term and long-term effects are significant,safe and feasible and it is worth further promotion.
作者
贾颖
JIA Ying(Taizhou People’s Hospital,Taizhou 225300,China)
出处
《中国医学创新》
CAS
2018年第29期101-104,共4页
Medical Innovation of China
关键词
沙丁胺醇
布地奈德
雾化吸入
小儿哮喘急性发作
Salbutamol
Budesonide
Aerosol inhalation
Acute asthma attack of children
作者简介
通信作者:贾颖。
