摘要
乳腺癌是女性常见的恶性肿瘤之一,居中国女性癌症发病首位,发病率和死亡率均呈上升趋势。三阴性乳腺癌(TNBC)是一种异质性疾病,较其他分型的乳腺癌具有发病年龄低,侵袭性强,复发和转移早的特点,目前尚缺乏标准治疗手段,疗效不佳,预后差,严重影响患者身心健康。文章总结和梳理TNBC的治疗现状和研究进展,以便提高对疾病的认识和治疗规范化水平。
Breast cancer is one of the most common female malignancies in China.The morbidity and mortality rate of breast cancer is rising.Triple-negative breast cancer(TNBC)is a heterogeneous disease,characterized with younger,more aggressive and easier recurrence or metastasis.Because there is no standard therapeutic regimen,TNBC has poor efficacy and prognosis,and seriously affects the patients′health.Summarizing and combing the status and progress of TNBC treatment can help us to better understand the disease and improve treatment.In addition,it inspires us to form new research ideas and explore the research directions of TNBC.
作者
周洁
陈萱
陈钰
陈道桢
ZHOU Jie;CHEN Xuan;CHEN Yu;CHEN Dao-zhen(Department of Central Laboratory,Wuxi Hospital for Maternal and Child Health Care Affiliated to Nanjing Medical University,Wuxi 214002,Jiangsu,China;Kangda College of Nanjing Medical University,Lianyungang 222023,Jiangsu,China)
出处
《医学研究生学报》
CAS
北大核心
2018年第8期853-858,共6页
Journal of Medical Postgraduates
基金
国家自然科学基金(81372480
81602728)
江苏省大学生创新创业训练计划项目(201713980001Y)
关键词
三阴性乳腺癌
化疗
靶向治疗
免疫治疗
内分泌治疗
triple-negative breast cancer
chemotherapy
targeted therapy
immunotherapy
endocrine therapy
作者简介
通信作者:陈道桢,E-mail:chendaozhen@163.com。
