摘要
目的:探讨分析经罗马Ⅲ、罗马Ⅳ标准确诊为功能性胃肠病(FGIDs)患者发生抑郁、焦虑的概率及其抑郁、焦虑程度与胃肠道症状分级的线性关系,为临床上进一步采取合理有效的针对性预防措施提供科学依据。方法:将120例2014年11月—2016年11月在我院确诊并接受治疗的功能性胃肠病患者作为观察组研究对象,同时采用随机数字表的方法选出120例健康体检的正常人群作为对照组研究对象。观察组和对照组研究对象均应用Zung式抑郁、焦虑自评量表进行评分并计算抑郁、焦虑发生率。观察组研究对象中抑郁及焦虑评分大于等于临界值者还应用肠道症状分级评分量表测评其胃肠道症状严重程度并分析二者之间的线性关系。结果:观察组中功能性消化不良、肠易激综合征、功能性便秘三种症状的研究对象其组间抑郁、焦虑的发生率比较差异不显著,发生率差异比较无统计学意义(P>0.05),但是均显著高于对照组研究对象抑郁、焦虑的发生率,其分别于对照组比较,差异显著,差别具有统计学意义(P<0.05)。抑郁评分与胃肠道症状严重程度评分的相关系数r=0.46,P<0.05;焦虑评分与胃肠道症状严重程度评分的相关系数r=0.64,P<0.05。表明观察组研究对象抑郁、焦虑程度与胃肠道症状分级均呈正相关,具有统计学意义。结论:功能性胃肠病患者的抑郁、焦虑发生率较高,且其胃肠道症状严重程度与抑郁、焦虑程度有关。
Objective:To explore and analyze the hierarchical linear relationship between the risk of depression,anxiety of patients with functional gastrointestinal disease(FGIDs)diagnosed with Roman III,Roman IV standard and to provide scientific basis for further taking reasonable and effective preventive measures in clinical practice.Methods:120 cases of patients with functional gastrointestinal disease treated in our hospital from November 2014 to November 2016 were selected as the research subjects of the observation group,at the same time,120 cases of healthy people who had physical examination in our hospital were randomly selected as the control group.The incidence of depression and anxiety of the observation group and the control group subjects were rated and calculated by applying Zung depression and anxiety self-assessment scale.The linear relationship between them and the severity of gastrointestinal symptoms was evaluated and analyzed by applying the intestinal symptoms severity classification rating scale for the subjects with depression and anxiety score greater than or equal to the critical value.Results:The incidence of depression,anxiety of the observation group in functional dyspepsia and irritable bowel syndrome and functional constipation symptoms of three kinds of subjects of study was of no significant difference(P>0.05),but they were significantly higher than those of the control group,the difference was statistically significant(P<0.05).The correlation coefficient between depression score and severity score of gastrointestinal symptoms was r=0.46,P<0.05.The correlation coefficient between anxiety score and severity score of gastrointestinal symptoms was r=0.64,P<0.05.The results showed that depression and anxiety were positively correlated with gastrointestinal symptoms and had statistical significance.Conclusions:The incidence of depression and anxiety was high in patients with functional gastrointestinal diseases,and the severity of gastrointestinal symptoms was related to depression and anxiety.
出处
《中医临床研究》
2018年第18期22-24,共3页
Clinical Journal Of Chinese Medicine
关键词
功能性胃肠病
抑郁
焦虑
胃肠道症状
严重程度
相关性研究
Functional gastrointestinal disease
Depression
Anxiety
Gastrointestinal symptoms
Severity
Correlation study
