摘要
目的研究托吡酯与卡马西平治疗脑梗死后继发癫痫的临床效果。方法选取140例脑梗死后继发癫痫患者作为研究对象,随机分为对照组和观察组,各70例。对照组给予卡马西平治疗,观察组给予托吡酯。对比治疗总有效率及不良反应发生率。结果观察组治疗总有效率(97.14%)高于对照组(72.86%),不良反应发生率(1.43%)低于对照组(18.57%),组间对比差异具有统计学意义(P<0.05)。结论在脑梗死后继发癫痫治疗过程中采用托吡酯效果优于卡马西平,疗效准确,且不良反应发生率较低,具有较高的临床推广价值。
Objective To study the clinical effect of topiramate and carbamazepine in the treatment of secondary epilepsy after cerebral infarction.Methods 140 patients with secondary epilepsy after cerebral infarction were selected as research object and randomly divided into control group and observation group,70 cases in each group.The control group was given carbamazepine treatment and the observation group was given topiramate.The total effective rate of treatment and the incidence of adverse reactions of two groups were compared.Results The total effective rate(97.14%)in the observation group was significantly higher than that in the control group(72.86%),and the incidence of adverse reactions was 1.43%,which was lower than the control group(18.57%).There was significant difference between the two groups(P<0.05).Conclusion Topiramate is more effective than carbamazepine in the treatment of secondary epilepsy after cerebral infarction.The curative effect is accurate and the incidence of adverse reactions is low,which has a high clinical value.
作者
殷卓琳
YIN Zhuolin(Department of Neurology,Jilin People's Hospital,Changchun Jilin 130021,China)
出处
《中国卫生标准管理》
2018年第8期86-87,共2页
China Health Standard Management
关键词
托吡酯
卡马西平
脑梗死
继发癫痫
Topiramate
Carbamazepine
cerebral infarction
secondary epilepsy
