摘要
目的:观察中药"四黄清灵液"熏蒸联合人工泪液治疗干眼症的临床疗效,为临床治疗干眼症提供依据。方法:选取2016-06/12我院眼科就诊的干眼患者82例164眼,随机分为对照组与观察组。对照组41例82眼给予人工泪液滴双眼,4次/d;观察组41例82眼在给予人工泪液基础上增加自拟中药"四黄清灵液"(黄精、黄岑、黄连、菊花、薄荷)熏蒸双眼,1次/d。治疗前及连续治疗14d后,分别观察两组患者泪膜破裂时间(break-up time,BUT)、角膜荧光素染色(corneal fluorescein staining,FL)、基础泪液分泌试验(SchirmerⅠtest,SⅠt)以判断疗效变化。结果:治疗14d后,观察组总有效率为87.8%,对照组总有效率为70.7%,两组之间比较差异有统计学意义(P<0.05)。治疗14d后观察组SⅠt(8.43±2.51mm/5min)、BUT(8.60±2.47s)较对照组(6.38±2.52mm/5min、6.35±2.29s)升高,差异有统计学意义(P<0.05);治疗14d后观察组FL评分(0.84±0.75分)低于对照组(1.26±0.84分),差异有统计学意义(P<0.05)。结论:自拟中药"四黄清灵液"熏蒸联合人工泪液治疗干眼疗效优于单纯使用人工泪液,可有效改善干眼症患者的临床症状。
AIM:To observe the clinical efficacy of fumigation treatment of traditional Chinese medicine(Four Yellow Qing Ling Water)for dry eye,and to provide the reference for clinical treatment of dry eye.METHODS:Totally 82 patients(164 eyes)were randomly divided into two groups from June 2016 to December 2016 in Ophthalmology Department of our hospital.The patients in control group were given artificial tears;the patients in the observation group were given artificial tears and fumigation treatment of traditional Chinese(Four Yellow Qing Ling Water)once a day.After treatment for 14d,the Schirmer Itest(SIt),break-up time(BUT),cornea fluorescein staining(FL)and clinical efficacy of two groups were compared.RESULTS:The efficiency rate of observation group was significantly better than the control group(87.8%vs 70.7%,P<0.5).The S It and BUT in the observation group were significantly higher than those in the control group(8.43~2.51mm/5min vs 6.38~2.52mm/5min,P<0.05;8.60~2.47s vs 6.35~2.29s,P<0.05);the FL in the observation group(0.84~0.75 vs 1.26~0.84,P<0.05)significantly lower than those in the control group.CONCLUSION:The fumigation treatment of traditional Chinese medicine(Four Yellow Qing Ling Water)combined with artificial tears for dry eyes can improve the clinical symptoms of dry eye syndrome.
作者
陈艳艳
黄冲
冯运红
罗远芳
黄秋花
姚馨蕙
金守梅
谢静
林媛红
邓刃锋
Yan-Yan Chen;Chong Huang;Yun-Hong Feng;Yuan-Fang Luo;Qiu-Hua Huang;Xin-Hui Yao;Shou-Mei Jin;Jing Xie;Yuan-Hong Lin;Ren-Feng Deng(Department of Ophthalmology,Longgang ENT Hospital,Shenzhen Institute of ENT,Shenzhen 518172,Guangdong Province,China;Shenzhen Longgang District of Traditional Chinese Medicine Hospital,Beijing University of Chinese Medicine Shenzhen Hospital,Shenzhen 518172,Guangdong Province,China)
出处
《国际眼科杂志》
CAS
北大核心
2018年第4期762-764,共3页
International Eye Science
基金
深圳市科技创新委员会基金(No.ZDSYS201506050935272)
龙岗区科技发展资金医疗卫生(扶持类)(No.20160607142024828,20160608104609244)
关键词
中药
中药熏蒸
人工泪液
干眼
traditional Chinese medicine
herbal fumigation
artificial tears
dry eye
作者简介
陈艳艳,主管护师,护士长,研究方向:眼部疾病的护理;通讯作者:冯运红,硕士,主任医师,眼科主任,研究方向:眼表疾病、白内障.homefyh@126.com
