摘要
从针灸对阿片肽、五羟色胺、神经胶质细胞、细胞因子、氨基酸及嘌呤类物质的影响入手探讨针灸治疗神经病理性疼痛(NP)的机制,指出针灸作为中医学特色疗法之一,在治疗神经病理性疼痛的临床疗效和安全性已被认可,然而其相关机制仍旧未完全阐明,可能与针灸能激活自身机体功能,对上述物质进行多层次、多靶点的调节有关。
The mechanismof acupuncture in treating neuropathic pain(NP)is discussed from the influence of acupuncture on opioid peptide,serotonin,glia cells,cytokine,amino acid and purine.it is pointed out that acupuncture as one of the TCM-feature therapies,its clinical effects and the safety of the therapy in treating NP have been approved,while the related mechanism is not elucidated completely,it might be related to acupuncture mobilizing body function,and regulating the substances all above frommultiple levels and multi targets.
作者
林元杰
吴耀持
郭晟
LIN Yuanjie;WU Yaochi;GUO Sheng(The 6th People's Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200233,China)
出处
《西部中医药》
2018年第1期138-142,共5页
Western Journal of Traditional Chinese Medicine
基金
上海市科研计划项目(编号14401971500)
关键词
神经病理性疼痛
针灸
动物实验
机理
neuropathic pain
acupuncture
animal experiment
the mechanism
作者简介
林元杰(1990—),男,在读硕士研究生。研究方向:腰椎间盘突出症的中西医结合治疗及其相关作用机理研究。;通讯作者:吴耀持(1961—),男,博士研究生导师,教授,主任医师。研究方向:腰椎间盘突出症的中西医结合治疗及其相关作用机理的研究。
