摘要
目的探讨经期静脉注射阿奇霉素治疗慢性附件炎的临床效果。方法选取宁波市鄞州区明州医院2016年1月~2017年7月收治的100例附件炎患者，按照随机数字表法分为研究组与对照组，各50例。对照组患者在经期结束之后第3天静脉滴注阿奇霉素，研究组患者在经期开始第1天静脉滴注阿奇霉素，比较2组患者临床治疗有效率、生活质量评分以及CD3+、CD4+、CD8+、CD4+/CD8+等免疫学指标。结果研究组临床治疗有效率96.00%，高于对照组的80.00%（P＜0.05）；治疗后研究组生活质量总评分（85.36±5.17）分，显著高于对照组的（75.31±5.02）分（P＜0.05）。治疗后，研究组患者免疫学指标中CD3+、CD4+、CD8+、CD4+/CD8+均较对照组明显改善，组间比较差异有统计学意义（P＜0.05）。结论临床中对于慢性附件炎患者经期静脉注射阿奇霉素治疗具有较好的临床效果，在提高患者的临床有效率外，对改善患者的机体免疫力方面效果显著，同时，能提高患者的生活质量。
Objective To investigate the clinical efficacy of intravenous azithromycin in the treatment of chronic adnexal inflammation.Methods100patients with adnexal inflammation from January2016to July2017were c were divided into the study group and the control group according to the random number table,50cases in each group.Patients in the control group were given azithromycin intravenously third days after the end of the menstrual cycle,and the patients in the study group were given azithromycin intravenously on the first day of the menstrual cycle.The clinical treatment efficiency,quality of life score and CD3+,CD4+,CD8+,CD4+,/CD8+and other immunological indexes were compared between the2groups.Results The effective rate of clinical treatment was(96.00%),higher than80.00%of the control group(P<0.05).Quality of life score in research group after treatment was(85.36±5.17)points,higher than(75.31±5.02)points of the control group(P<0.05).After treatment,CD3+,CD4+,CD8+and CD4+/CD8+in the study group were all lower than those in the control group(P<0.05).Conclusion For clinical chronic adnexitis patient period of intravenous azithromycin therapy has good clinical effect,improve clinical efficiency in patients,to improve the patient’s machine Significant in body immunity.At the same time,improve the quality of life of patients.
作者
葛莉红
徐佳玲
GE Li-hong;XU Jia-ling(Department of Gynecology, Yinzhou District Mingzhou Hospital of Ningbo City, Ningbo 315100, China)
出处
《中国生化药物杂志》
CAS
2017年第12期171-173,共3页
Chinese Journal of Biochemical Pharmaceutics
关键词
慢性附件炎
阿奇霉素
血流动力学
生活质量
chronic adnexal inflammation
azithromycin
hemodynamics
quality of life
作者简介
葛莉红，女，本科，主治医师，研究方向：妇科炎症诊治，E-mail：zjglh2017111@163.com。
