摘要
目的:探讨脑胶质瘤患者血清IL-6、IL-8、IL-10和TNF-α的表达和临床意义。方法:收治脑胶质瘤患者120例,低级别脑胶质瘤患者60例为对照组,高级别脑胶质瘤患者60例为观察组,检测两组患者的血清IL-6、IL-8、IL-10和TNF-α的含量。结果:观察组血清IL-6、IL-10以及TNF-α含量明显高于对照组,两组差异有统计学意义(P<0.05);IL-6、IL-10和TNF-α联合检测时其受试者工作特征曲线下面积,灵敏性及特异性均高于单独检测。结论:采用IL-6、IL-10和TNF-α联合诊断比单项指标诊断价值更佳。
Objective:To investigate the expression and clinical significance of serum IL-6,IL-8,IL-10 and TNF-α in patientswith brain glioma.Methods:120 patients with brain glioma were selected.60 patients with low grade glioma were selected as thecontrol group.60 patients with high-grade glioma were used as the observation group.The serum levels of IL-6,IL-8,IL-10 andTNF-α were detected in two groups of patients.Results:The serum levels of IL-6,IL-10 and TNF-α in the observation groupwere significantly higher than those in the control group,and the differences between groups were significant(P<0.05).The areaunder the receiver-operating characteristic curve,sensitivity and specificity of the combined detection with IL-6,IL-10 andTNF-α were higher than single detection.Conclusion:The combined diagnosis of IL-6,IL-10 and TNF-α is better than thesingle indicator.
作者
黄文辉
Huang Wenhui(The Second Affiliated Hospital of Guangzhou Medical University 510260)
出处
《中国社区医师》
2016年第17期118-118,120,共2页
Chinese Community Doctors
基金
基于社区高血压信息化管理的脑出血早期预警分级干预研究
基金编号:C2015035~~
