摘要
目的:分析中医药治疗中晚期结直肠恶性肿瘤用药规律。方法:基于医院门诊信息系统的真实世界临床数据,提取2014年1月至2015年7月南京中医药大学附属医院门诊就诊的中晚期结直肠恶性肿瘤患者中药处方。结果:共收集2444首治疗结直肠恶性肿瘤中药处方,计654味中药,用药频次50,240次;使用频次前30位的中药中补益药12味,消食药5味,清热药3味,理气药3味,健脾药2味,活血药1味,止血药1味,化痰药1味,收敛药1味;药物核心组合:茯苓(丁),白术(麸炒),陈皮,薏苡仁(生),甘草(炙),莪术(醋制)。结论:中晚期结直肠恶性肿瘤中医药治疗大多采用全力扶正、精准攻毒的中医抗癌策略。
Objective： To analyze the clinical medication features for advanced colorectal cancer. Methods：Real world data based on Hospital Information System were collected from January 2014 to July 2015. Results：Data of 2444 prescriptions with colorectal cancer were collected, including 654 herbs and 50,240 frequency. The top 30 herbs included the 12 qi-reinforcing and blood-enriching drugs, 5 indigeation drugs, 3 heat-clearing drugs, 3 qi-regulating drugs, 2 spleen-strengthening drugs, 1 drug used to activate blood flow, 1 hemostatic drug, 1 expectorant drug, 1 astringent drug. Drugs core combination： Fuling（poria）, Baizhu（bighead atractylodes rhizome）, Chenpi（bighead atractylodes rhizome）, Yiyiren（Semen Coicis）, Zhigancao（prepared Radix Glycyrrhizae）,Ezhu（Curcuma zedoaria Rosc）. Conclusion： Traditional Chinese medicine（TCM） treatment of advanced colorectal cancer mostly adopts the strategy of strengthening the body and accurately attacking toxins.
作者
周青
商洪涛
吴本升
陈玉根
ZHOU Qing;SHANG Hong-tao;WU Ben-sheng;CHEN Yu-gen(The Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing Jiangsu 210029,China;Suzhou Affiliated Hospital of Nanjing University of Chinese Medieine,Suzhou Jiangsu 215001,China)
出处
《中医药导报》
2018年第21期32-36,共5页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
基金
江苏省中医科研专项-省名中医治疗大肠癌用药特点与规律初步研究(ZX2016C2)
关键词
真实世界
结直肠恶性肿瘤
中晚期
中医药
用药规律
临床疗效
real world research
colorectal cancer
advanced
traditional Chinese medicine
medieation rules efficacy
作者简介
通讯作者：陈玉根，E—mail：yugen.chen@njucm．edu．cn
