摘要
目的:分析经直肠超声(TRUS)前列腺穿刺活检联合血清PSA指标对前列腺癌的诊断价值。方法:将180例疑似前列腺癌患者纳入研究检测血清前列腺特异抗原(PSA)水平,行TRUS前列腺穿刺活检。观察总PSA(T-PAS)、游离PSA(F-PSA)、F/T-PSA及PSA密度(PSAD)在不同前列腺疾病组及不同超声分型前列腺癌中的水平,分析不同前列腺癌分型在超声下的图像特征。对比非癌症组与癌症组血流分级。结果:前列腺癌组T-PAS、F-PSA、PSAD水平为3组最高,F/T-PSA为三组最低。结节型、隐匿型组T-PSA、FPSA、PSAD均低于弥漫浸润结节型和弥漫浸润型;前列腺癌组血流分级2、3级率(69. 23%)均高于非前列腺癌组(14. 94%),差异具有统计学意义(all P <0. 05)。结论:血清PSA联合直肠超声前列腺疾病有利于区分前列腺癌和前列腺增生,帮组分型,有重要诊断价值。
Objective： To analyze the diagnostic value of transrectal ultrasound（ TRUS） prostate biopsy combined with serum PSA markers in prostate cancer. Methods： A total of 180 patients with suspected prostate cancer were enrolled in this study. Serum prostate specific antigen（ PSA） levels were detected and TRUS prostate biopsy was performed. The levels of total PSA（ T-PAS）,free PSA（ F-PSA）,F/T-PSA and PSA density（ PSAD）in different prostate diseases and different types of prostate cancer were observed,and the image features of different types of prostate cancer under ultrasound were analyzed. The blood flow classification between non-prostate cancer group and prostate cancer group was compared. Results： The levels of T-PAS,F-PSA and PSAD in the prostate cancer group were the highest in the 3 groups,and F/T-PSA was the lowest in the three group. The T-PSA,F-PSA and PSAD of nodular and occult group were lower than those of diffuse infiltrative nodule type and diffuse infiltrative type; the blood flow classification rate of grade 2 and grade 3 in prostate cancer group（ 69. 23%） was higher than that of non-prostate cancer group（ 14. 94%）, all with statistically significant differences（ all P〈0. 05）.Conclusions： Serum PSA combined with TRUS is helpful to distinguish prostate cancer from benign prostatic hyperplasia and the classification of prostate cancer,which has important diagnostic value.
作者
雷星辉
车兴奎
刘咏松
何涛
马强
张婕
LEI Xinghui;CHE Xingkui;LIU Yongsong;HE Tao;MA Qiang;ZHANG Jie(Department of Urology,Yibin Second People＇s Hospital,Yibin 644000,Sichuan,China;Department of Radiology,Mianyang Third People＇s Hospital,Mianyang 621000,Sichuan,China)
出处
《中国性科学》
2018年第10期8-10,共3页
Chinese Journal of Human Sexuality
基金
四川省卫生和计划生育委员会科研课题项目(17PJ413)
关键词
经直肠超声引导
前列腺癌
穿刺活检
血清前列腺特异抗原
Transrectal ultrasound （TRUS） guidance
Prostate cancer
Biopsy
Serum prostate specific antigen
作者简介
雷星辉（1970-），男，副主任医师，主要研究方向为泌尿系肿瘤的临床诊治,通讯作者，E-mail：yb-lxh@163．com
