摘要
目的分析厄贝沙坦联合苯磺酸氨氯地平治疗老年糖尿病合并高血压伴高尿酸血症的临床疗效及应用价值。方法选取105例老年糖尿病合并高血压伴高尿酸血症患者作为研究对象,采用随机分组法均分为3组,将单纯使用厄贝沙坦进行治疗的患者作为厄贝沙坦组;将单纯使用苯磺酸氨氯地平治疗的患者作为苯磺酸氨氯地平组;将采用上述两种药物进行联合治疗的患者作为联合组。分析并对比三组不同用药方案下血压、血尿酸水平变化的差异。结果联合组治疗总有效率显著高于厄贝沙坦组与苯磺酸氨氯地平组(P<0.05);三组经治疗后血压水平均显著降低,联合组降低程度显著高于其他两组(P<0.05);联合组与厄贝沙坦组经治疗后血尿酸水平均显著降低(P<0.05)。结论针对糖尿病合并高血压伴高尿酸血症的老年患者进行临床治疗时,采用厄贝沙坦与苯磺酸氨氯地平联合用药可有效改善患者多项临床症状,疗效较为显著,且安全性较高,值得临床推广应用。
Objective To analyze the clinical efficacy and value of irbesartan combined with amlodipine besylate in the treatment of diabetes mellitus complicated with hypertension and hyperuricemia. Methods 105 patients with senile urinary disease complicated with hypertension and hyperuricemia were selected as study subjects and randomly divided into 3 groups. Patients treated with irbesartan alone were treated as irbesartan group; Patients treated with amlodipine besylate were treated as amlodipine besylate group; patients who were treated with the combination of the above two drugs were used as a combination group. Analyze and contrast the differences in blood pressure and blood uric acid levels among the three groups of different drug regimens. Results The total effective rate of the combined group was significantly higher than that of the irbesartan group and the amlodipine besylate group（P〈0.05）; The blood pressure levels of the three groups after treatment were significantly lower, and the degree of reduction in the combined group was significantly higher than that of the other two groups（P〈0.05）; The uric acid levels in the combination group and irbesartan group were significantly lower（P〈0.05）. Conclusion In the clinical treatment of elderly patients with diabetes mellitus complicated with hypertension and hyperuricemia, the combination of irbesartan and amlodipine besylate can effectively improve the patient＇s clinical symptoms, the efficacy is more significant, and the safety is higher, worthy of clinical application.
作者
李玲
LI Ling(The Sixth Community Health Service Center of Shihezi,Shihezi,Xinjiang,83200)
出处
《智慧健康》
2018年第10期69-71,共3页
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