摘要
目的分析宫颈癌患者根治术后发生医院感染的病原菌分布及引起医院感染的影响因素,为宫颈癌根治术后防治感染提供相关临床依据。方法选取2016年3月-2017年7月医院收治的162例宫颈癌根治术患者,观察和记录患者医院感染率、感染部位分布、病原菌分布等结果,并进行单因素及多因素Logistics回归分析患者术后发生医院感染的影响因素。结果 162例患者术后发生医院感染35例,感染发生率为21.60%,感染部位以手术切口感染为主;35例感染患者共检出病原菌42株,其中革兰阴性菌21株占50.00%;多因素Logistics回归分析结果显示,患者年龄≥60岁、合并糖尿病、住院时间≥14d、引流管放置时间≥7d、导尿管留置时间≥14d、手术路径为开腹手术、接受化疗以及合并贫血状态为宫颈癌患者根治术后发生医院感染的独立影响因素。结论宫颈癌患者根治术后发生医院感染较为常见,感染病原菌以革兰阴性菌为主,引发感染的影响因素较多,要重视并采取针对性措施加强术后感染的防治。
OBJECTIVE To investigate the distribution of pathogens causing postoperative nosocomial infections in cervical cancer patients undergoing radical surgery and analyze the influencing factors for the nosocomial infections so as to provide guidance for clinical prevention and treatment of the nosocomial infections.METHODS A total of162 patients with cervical cancer who were treated in hospitals from Mar 2016 to Jul 2017 were enrolled in the study.The incidence of nosocomial infections,distribution of infection sites and species of pathogens were observed and recorded.The univariate analysis and multivariate logistic regression analysis were performed for the influencing factors for the postoperative nosocomial infections.RESULTS Of the 162 patients,35 had nosocomial infections,with the infection rate 21.60%;the surgical incision was the major infection site.Totally 42 strains of pathogens were isolated from the 35 patients with infections,21（50.00%）of which were gram-negative bacteria.The result of multivariate logistic regression analysis showed that the independent influencing factors for the postoperative nosocomial infections in the cervical cancer patients included no less than 60 years of age,complication with diabetes mellitus,length of hospital stay no less than 14 days,time of drainage tube indwelling no less than 7 days,time of urinary catheter indwelling no less than 14 days,laparotomy,chemotherapy and complication with anemia.CONCLUSIONThe postoperative nosocomial infection is very common among the cervical cancer patients undergoing radical surgery,the gram-negative bacteria are dominant among the pathogens causing the infections.There are a variety of influencing factors for the infections.It is necessary to take targeted measures so as to prevent the postoperative nosocomial infections.
作者
何绍民
石新荷
徐晓琴
俞小英
邓娅
HE Shao-min;SHI Xin-he;XU Xiao-qin;YU Xiao-ying;DENG Ya(Second Hospital of Shaoxing City,Shaoxing,Zhejiang 312000,China)
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2018年第17期2663-2666,共4页
Chinese Journal of Nosocomiology
关键词
宫颈癌
术后
感染
病原菌
危险因素
Cervical cancer
Postoperative
Infection
Pathogen
Risk factor
