摘要
目的探讨内镜黏膜下剥离术和切除术治疗早期上消化道肿瘤的临床效果。方法将早期上消化道肿瘤患者186例作为研究对象,按照患者入院顺序和相关手术指征分为研究组102例,对照组84例,研究组患者行内镜下黏膜切除术(EMR),对照组患者给予内镜下粘膜剥离术(ESD),观察两组患者的临床疗效。结果研究组患者完全切除率为91. 18%(93/102),对照组为96. 43%,差异具有统计学意义(P <0. 05);研究组患者出血、穿孔并发症发生率为15. 69%(16/102),与对照组16. 67%(14/84)比较,差异不显著(P> 0. 05);研究组患者随访6个月复发率为2. 94%(3/102),与对照组2. 38%(2/84)比较差异不显著(P> 0. 05),两组患者住院时间比较差异不显著(P> 0. 05)。结论内镜下粘膜切除术和粘膜剥离术均是治疗早期上消化道肿瘤的有效方法,疗效可靠,安全性高,可在临床范围内推广使用。
Objective To investigate the clinical effect of endoscopic submucosal dissection and resection in the treatment of early digestive tract tumors. Methods 186 cases of early gastrointestinal cancer patients as the research object,according to the order of admission of patients and surgical indications were divided into the study group of 102 cases,84 cases in the control group,patients in the study group were treated with endoscopic mucosal resection（EMR）,the control group were treated with endoscopic.Submucosal dissection（ESD） treatment,observe the clinical efficacy of the 2 groups. Results In the tudy group,complete resection rate was 91.18%（93/102）,the control group was 96.43%,the difference was statistically significant（ P〈0.05）; in the study group,hemorrhage and perforation complication rate was 15.69%（16/102）,and 16.67% in the control group（14/84）,the difference was not significant（ P〉0.05）;In the study group,6 month,recurrence rate was 2.94%（3/102）,and 2.38% in the control group（2/84）.There was no significant difference（ P〉0.05）,hospitalized time of the 2 groups.Had no significant difference（ P〉0.05）. Conclusion EMR and ESD are effective methods for early stage of upper gastrointestinal tract.The curative effect is reliable and safe.It can be widely used in clinical practice.
作者
薛麟
华鹏
高原
XUE Lin;HUA Peng;GAO Yuan(Ankang Central Hospital,Ankang,72500)
出处
《实用癌症杂志》
2018年第10期1690-1692,共3页
The Practical Journal of Cancer
关键词
早期上消化道肿瘤
内镜下黏膜剥离术
内镜下黏膜切除术
Early digestive tract tumor
Endoscopic submucosal dissection
Endoscopic mucosal resection
作者简介
通讯作者：高原
