摘要
目的探讨PCT、WBCN%、CRP、ESR、血培养、痰培养联合检测在儿科重症肺炎中应用价值,以减少对重症肺炎患儿的误诊和漏诊并可以得到及时的治疗。方法选取山东大学附属省立医院2016年收治的196例儿科肺炎患儿为研究对象,其中90例为重症肺炎,106例为轻度肺炎;根据血培养或痰培养结果分为细菌性肺炎55例、病毒性肺炎65例和其他肺炎76例,采集患儿的血液分别检测降钙素原(PCT)、白细胞计数百分比(WBCN%)、C反应蛋白(CRP)、红细胞沉降率(ESR),观察各组患儿的PCT、WBCN%、CRP、ESR水平以及PCT、WBCN%、CRP、ESR检测的灵敏度、特异性等指标。结果重症肺炎患儿的PCT、WBCN%、CRP、ESR水平明显高于轻度肺炎患儿,差异有统计学意义(P<0.05);细菌性肺炎患儿的PCT、WBCN%、CRP、ESR水平明显高于病毒性肺炎患儿和其他肺炎患儿,差异有统计学意义(P<0.05)。PCT检测的灵敏度、特异性等指标明显高于WBCN%、CRP、ESR,差异有统计学意义(P<0.05)。结论 PCT、WBCN%、CRP、ESR、血培养、痰培养联合检测可以准确地判断儿科重症肺炎的发病情况,而且PCT检测的灵敏度、特异性比其他更可靠。
Objective To explore the application value of combined detection of procalcitonin（ PCT）,WBCN%,C-reaction protein（ CRP）,erythrocyte sedimentation rate（ ESR）,blood culture,and sputum culture in children with severe pneumonia,reduce misdiagnosis and missed diagnosis of severe pneumonia in children,provide timely treatment. Methods A total of 196 children with pneumonia treated in Shandong Provincical Hospital Affiliated to Shandong University in 2016 were selected as study object,then they were divided into severe pneumonia group（ 90 children） and mild pneumonia group（ 106 children）. According to the results of blood culture or sputum culture,the children were divided into bacterial pneumonia group（ 55 children）,viral pneumonia group（ 65 children）,and other pneumonia group（ 76 children）. Blood samples were obtained to detect PCT,WBCN%,CRP,and ESR. PCT,WBCN%,CRP,ESR levels and the sensitivities and specificities of PCT,WBCN%,CRP,ESR in different groups were observed. Results The levels of PCT,WBCN%,CRP,and ESR in severe pneumonia group were statistically significantly higher than those in mild pneumonia group（ P〈0. 05）. The levels of PCT,WBCN%,CRP,and ESR in bacterial pneumonia group were statistically significantly higher than those in viral pneumonia group and other pneumonia group（ P〈0. 05）. The sensitivity and specificity of PCT were statistically significantly higher than those of WBCN%,CRP,and ESR（ P〈0. 05）. Conclusion Combined detection of PCT,WBCN%,CRP,ESR,blood culture,and sputum culture used in children with severe pneumonia can accurately determine the prevalence of severe pneumonia,the sensitivity and specificity of PCT is more reliable compared with other indexes.
作者
郝青
刘义庆
HAO Qing;LIU Yi-Qing(Department of Clinical Laboratory,Shandong Provincical Hospital Affiliated to Shandong University,Ji＇nan,Shandong 250002,China)
出处
《中国妇幼保健》
CAS
2018年第16期3706-3708,共3页
Maternal and Child Health Care of China
