摘要
单味药及其有效成分、中药复方及中成药对血管的促进、抑制作用为目前研究热点,但中药对脑缺血后促进血管生成的作用及机制相关研究尚未深入。本文对中药促进脑血管生成的中医理论、体外研究、在体研究进行综述,并对通过Notch和Wnt信号通路调控血管生成的机制研究进行重点阐述,为药理作用机制研究及新药研发提供参考。
The promotion or inhibition of blood vessels by TCM, active ingredients of TCM, TCM compounds, and Chinese patent drugs is currently a research hotspot, with relatively abundant research. However, the study of the role and profound mechanism of TCM on angiogenesis after cerebral ischemia is relatively rare. Therefore, this article reviewed theories, in vitro studies and in vivo studies on the promotion of cerebral angiogenesis by TCM, and summarized the studies on TCM regulation of angiogenesis through Notch and Wnt signaling pathway mechanisms, with a purpose to provide references for resarch on related mechanisms and development of new deugs.
作者
黄生辉
李妍怡
巩婷
HUANG Sheng-hui;LI Yan-yi;GONG Ting(Cooperation of Chinese and Western Medicine College,Gansu University of Chinese Medicine,Lanzhou 730000,China;Department of Neurology,Affiliated Hospital of Gansu University of Chinese Medicine,Lanzhou 730000,China;Department of Encephalopathy,Gansu Provincial Hospital of Traditional Chinese Medicine,Lanzhou 730050,China)
出处
《中国中医药信息杂志》
CAS
CSCD
2018年第7期137-140,共4页
Chinese Journal of Information on Traditional Chinese Medicine
基金
国家自然科学基金(81460686)
作者简介
通讯作者：李妍怡,E-mail：534044812@qq.com
