摘要
目的探讨孕期教育联合营养干预对妊娠期糖尿病(GDM)患者体重增长、免疫功能及新生儿体重功能的影响。方法选择2013年3月~2017年3月南通大学第四附属医院收治的GDM患者96例,根据就诊顺序随机分为对照组(46例)和观察组(50例)。对照组给予常规产检和教育,观察组在对照组基础上给予孕期综合教育和营养干预。比较两组孕妇体重增长情况、细胞免疫功能及新生儿体重情况。结果观察组患者孕期体重增长[(13.7±2.4)kg]低于对照组[(17.1±2.7)kg],差异有统计学意义(P<0.05);观察组新生儿体重[(3.21±0.71)kg]明显低于对照组[(3.85±0.83)kg],差异有统计学意义(P<0.05);妊娠末期观察组患者的CD3^+、CD4^+及CD4^+/CD8^+水平明显高于对照组,而CD8则明显低于对照组,差异有统计学意义(P<0.05)。结论孕期教育联合营养干预可有效控制GDM患者体重增长,改善细胞免疫功能,并能有效控制新生儿体重。
Objective To investigate the effect of prenatal education combine nutrition intervention on maternal and infant weight and immune function in patients with gestational diabetes mellitus. Methods From March 2013 to March2017, 96 cases of gestational diabetes patients diagnosed in the Fourth Affiliated Hospital of Nantong University were randomly divided into control group（46 cases） and observation group（50 cases）. The control group was given routine examination and routine health education. The observation group was given comprehensive prenatal education combine nutrition intervention besides routine examinations and health education. Maternal weight gain, immune function and neonatal weight were compared between the two groups. Results Maternal weight gain in observation group was（13.7±2.4） kg, significantly lower than that in control group [（17.1±2.7） kg], and the difference was statistically significant（P〈0.05）. Neonatal weight in observation group was（3.21±0.71） kg, which was obviously lower than that in control group[（3.85±0.83） kg], and the difference was statistically significant（P〈0.05）. At the end of pregnancy, levels of CD3^＋, CD4^＋ and CD4^＋/CD8^＋ in observation group were significantly higher than those in control group, while CD8^＋ was significantly lower than control group, and the differences were all statistically significant（P〈0.05）. Conclusion Prenatal education combined nutritional intervention have significant effect on maternal weight gain and neonatal weight, and it could effectively improve the immune function in patients with gestational diabetes mellitus.
作者
朱燕
王坚青
薛金玲
ZHU Ya, WANG Jianqing, XUE Jingling(Department of Obstetrics and Gynecology, the Fourth Affiliated Hospital of Nantong University, Jiangsu Province, Yancheng 224005, Chin)
出处
《中国医药导报》
CAS
2018年第15期111-114,共4页
China Medical Herald
关键词
孕期教育
营养干预
妊娠糖尿病
母婴结局
Prenatal education
Nutritional intervention
Gestational diabetes mellitus
Maternal-fetal outcome
作者简介
朱燕（1988．7-），女，硕士，主要从事围生医学相关的临床工作。;[通讯作者]薛金玲（1964．3-），女，主任医师，主要从事妇产医学相关的临床工作。
