摘要
目的:观察低频r TMS治疗对于卒中后运动功能障碍恢复的作用,同时观察脑出血患者低频r TMS治疗的安全性。方法:选取75例患者,采用随机数字表法随机分组:对照组(n=39),治疗组(n=36)。2组患者均予常规康复训练,治疗组除常规康复治疗外,予健侧M1区低频r TMS治疗,每日1次,共20天。治疗前后分别对各组患者进行FuglMeyer评分(包括上肢及下肢评分)、FIM、Berg评分。结果:(1)Fugl-Meyer评分:治疗后2组患者Fugl-Meyer评分均升高,与对照组相比,治疗组评分(特别是上肢评分)升高更明显(P<0.05)。(2)Berg评分:2组患者在治疗后Berg评分较治疗前均有升高,且治疗组明显高于对照组(P<0.05)。(3)FIM评分:2组患者在治疗后FIM评分较治疗前均有升高,但是2组未显示显著性差异(P>0.05)。(4)安全性:治疗过程中所有观察对象均未出现不良反应,安全性较好。结论:健侧M1区低频r TMS能明显提高卒中后患者偏瘫肢体的运动功能及平衡功能,对上肢功能作用更显著,且治疗安全性好。
Objective: To study the effect of low frequency repetitive transcranial magnetic stimulation (rTMS) on dyskinesia in stroke patients, and its safety for patients with cerebral hemorrhage. Method: Seventy-five stroke patients were randomly assigned to treatment group(n=36)and control group(n=39).Both groups received conventional rehabilitation, and the treatment group received rTMS in M1 region,once a day, a total of 20 days. Both groups were assessed with Fugl-Meyer Assessment (FMA),Functional Independence Measure(FIM)and Berg before and after treatment. Result: ①Fugl-Meyer Assessment:Fugl-Meyer scores of the 2 groups were both elevated after treatment. Compared with the control group,the treatment group score for the upper limb increased more significantly (P〈0.05). ②Berg scale:The scores of Berg scale in 2 groups were higher than those before treatment,and the treatment group was significantly higher than the control group(P〈0.05). ③FIM: The post treatment scores of FIM in 2 groups were higher than those before treatment, however, no significant difference was found between the 2 groups(P〉0.05). ④Safety: No side-effects were observed during treatment, and the safety is good. Conclusion: rTMS is safe and can improve motor function (especially for upper limb) and balance function significantly for stroke patients.
作者
赵晓琳
刘天龙
周禹鑫
张立新
ZHAO Xiaolin;LIU Tianiong;ZHOU Yuxin;et al.(Rehabilitation Center of Shengjing Hospital of China Medical University, 110000)
出处
《中国康复医学杂志》
CAS
CSCD
北大核心
2018年第7期800-805,共6页
Chinese Journal of Rehabilitation Medicine
关键词
脑卒中
重复经颅磁刺激
运动障碍
stroke
transcranial magnetic stimulation
dyskinesia
作者简介
赵晓琳,女,硕士研究生,住院医师;通讯作者