摘要
从西方医学的传入及其对中药研究的影响,阐述中药现代技术研究的初衷与开端;从基源、性状、理化及计算机辅助鉴别方面分析中药鉴定的研究现状,并从中药化学成分、中药药学作用两方面概述中药药效物质基础研究的发展。现状表明:中药现代药效学研究与传统中药理论关联度低,与中医临床用药的整体观思路不合拍,值得我们反思和改进;未来研究应积极探索保持中医特色,充分发挥中医整体观念和辨证论治的长处,使中药的现代研究与更高层次上传统中药理论实现统一。
From the introduction of western medicine and its influence on the research of Chinese materia medica,the original intention and beginning of modern technology research of Chinese materia medica are expounded. The research status of identification of Chinese materia medica is analyzed from the aspects of source,character,physicochemistry and computer aided identification,and the research development of material basis of Chinese materia medica is summarized from their chemical compositions and pharmacological actions. The present situation shows that there is a low relationship between the modern pharmacodynamic study of Chinese materia medica and the theory of traditional Chinese medicine,and it is not compatible with the holism concept in clinical medication of traditional Chinese medicine,which is worth our reflection and improvement. The future research should actively explore the characteristics of traditional Chinese medicine,and give full play to the advantages of holism concept and treatment based on syndrome differentiation,so as to achieve the unification of modern research on Chinese materia medica and theory of traditional Chinese medicine at a higher level.
作者
俞仲毅
余国姗
YU Zhongyi;YU Guoshan(Experiment Center for Science and Technology ,Shanghai University of Traditional Chinese Medicine ,Shanghai 201203, China)
出处
《上海中医药大学学报》
CAS
2018年第3期1-8,共8页
Academic Journal of Shanghai University of Traditional Chinese Medicine
基金
国家自然科学基金资助项目(81473366)
关键词
中药研究
中药鉴定
药效物质
整体观
research of Chinese materia medica
identification of Chinese materia mediea
effective substances
holism concept
作者简介
俞仲毅，男，博士，研究员，主要从事中药药性理论基础研究 俞仲毅，1957年生，上海人。上海中医药大学研究员，硕士研究生导师。1983年毕业于黑龙江中医学院中医系，2004年获上海中医药大学博士学位。长期坚持在中药实验研究和中医临床第一线，曾参与《中华本草》《中药新药研制开发技术与方法》《现代中药学大辞典》《中国药物大词典》等的编撰工作；承担和主持国家自然科学基金、国家“十一五”支撑计划项目及主持或参与其他纵向或横向课题数十项．发表科研论文数十篇。在科学研究中尽量保持中医药整体性特点是其主要的学术思想。研究中坚持中药的整体性、生命体的整体性和中医药基本概念的整体性，着重以生命体整体的有序结构和化学组成的动态变化作为中医药研究的主要切入点．并探索两者之间以及与中医药理论的联系；发现了与中医药脏腑证候概念相对的中药性味归经等作用对象具有“泛组织”性质，并认为中医药研究的目的是寻找中医药理论的微观依据、发展自身的医学理论。
