摘要
目的分析本实验室在2010—2017年间参加的5次食品基质及3次人体基质中典型全氟有机化合物国际比对考核结果,探讨其在质量控制中的应用。方法使用Z评分法,分析全氟有机化合物及其典型异构体的考核结果,并结合样品测定数据,探讨测定方法的质量控制的关键点。结果绝大多数全氟有机化合物及其典型异构体的比对考核数据∣Z∣<1,考核结果满意。结论通过对参加全氟有机化合物的国际比对考核结果分析,可以及时发现检测过程中存在的问题,提高测定数据的准确性,为我国开展膳食中全氟有机化合物及其典型异构体的膳食暴露和人体负荷水平研究提供了有力保障。
Objective To analyze the result of global intercalibration study of typical perfluoroalkyl substances（ PFASs） and their typical isomers in foods,human milk and serum from 2010 to 2017 and discuss the application of the result in quality assurance and control. Methods Z-scores were employed to assess the result of PFASs and their typical isomers from global intercalibration study. Combined with the concentrations of the samples,we have also analyzed the key point of the method. Results The absolute values of the Z-scores of most PFASs and their typical isomers were less than 1,indicating that the concentrations determined by our laboratory were satisfactory. Conclusion The problems in the method could be found in time by participating in the global intercalibration study. Therefore we can improve the method to ensure the accuracy of the data and provide the effective technical support for determining the levels of PFASs and their typical isomers in foods,human milk and serum in China.
作者
王雨昕
李敬光
赵云峰
吴永宁
Wang Yuxin;Li Jingguang;Zhao Yunfeng;Wu Yongning(Key Laboratory of Food Safety Risk Assessment, Ministry of Health, China National Center for Food Safety Risk Assessment, Beijing 100021, China)
出处
《卫生研究》
CAS
CSCD
北大核心
2018年第3期453-458,共6页
Journal of Hygiene Research
基金
国家自然科学基金重点项目(No.21537001)
关键词
全氟有机化合物
支链/直链异构体
比对研究
质量控制
perfluoroalkyl substances
branched/linear isomers
intercalibration study
quality assurance and control
作者简介
王雨昕，女，硕士，助理研究员，研究方向：污染物暴露评估，E—mail：wangyx@cfsa．net．cn;通信作者：李敬光，男，博士，研究员，研究方向：污染物暴露评估，E—mail：lijg@cfsa．net．cn
