摘要
目的糖尿病前期(prediabetes,PD)发病率近年来逐渐升高,探讨虎门地区中老年人群糖尿病前期(PD)的患病率及筛选其危险因素,可为制定PD防治策略提供依据。方法采用随机分层抽样方法抽取2016年1—12月在东莞市虎门镇10个社区健康体检的1 050人,按血糖水平分为正常糖耐量(normal glucose tolerance,NGT)组、糖尿病前期(PD)组和糖尿病(diabetes mellitus,DM)组,应用调查量表收集研究对象的人口学和体查资料,采用全自动生化分析仪检测空腹血糖、甘油三酯(TG)、低密度脂蛋白(LDL)、血清尿酸(SUA)和糖化血红蛋白(Hb A1c)等指标。用率统计PD和DM的患病率以及多因素Logistic回归分析法筛选PD危险因素。结果共有1 002人完成调查,合格率为95.43%,PD和DM的患病率分别为23.95%和7.88%,PD患者Hb A1c升高患病率为55.00%。PD患者的SUA、TG、LDL和Hb A1c高于NGT人群(均P<0.05)。Logistic分析显示年龄、家庭收入、既往病史、体重指数(BMI)、腰围、TG、LDL和SUA为PD的危险因素,教育程度和体育锻炼为PD保护因素。结论虎门地区中老年人群PD患病率较高,可根据PD的危险因素和保护因素尽早制定PD防治方案以阻断糖尿病发生。
Objective The incidence of prediabetes is increasing year by year in recent years, this paper is to investigate the prevalenc of prediabetes and its related risk factors among the middle-aged and elderly people in Humen area to pro- vide the evidence for prevention and cure strategy of prediabetes. Methods One thousand and fifty volunteers were col- lected by stratified sampling randomly in Humen from January to December in 2016, who were divided into normal glu- cose tolerance （NGT） group, pre diabetes （PD） group and diabetes （DM） group according to their blood glucose lev- els. The demography and medical examination databases of volunteers were gathered by questionnaire, The levels of blood-fasting sugar, triglyeride （TG）, low density lipoprotein （LDL）, serum uric acid （SUA） and glycosylated hemo- globin lc （HbAl c） in serum were tested by automatic biochemistry analyzer. The prevalence of prediabetes and diabetes mellitus were analyzed by rate, the risk factors of prediabetes were analyzed Logistic regression. Results One thousand and two people had completely finished the questionnaire, the qualified rate was 95.43%, the prevalencs of prediabetes, diabetes mellitus were and HbAlc step up in prediabetes were 23.95% , 7.88% and 55.00% respectively. The levels of SUA, TG, LDL and HbAle in patients with PD were higher than that in NGT people （P 〈0.05）. Logistic regression a- nalysis showed that aging, family income, past history of illness, body mass indexes （ BMI）, waistline, TG, LDL and SUA were the independent risk factors for prediabetes. However, the educational level and physical exercise were the pro- tective factors factor for prediabetes. Conclusion The prediabetes is highly prevalent in the middle-aged and elderly population in Humen. We should make the prevention and cure schema as eariy as possible according to the prediabetes risk factors and protective factors so as to stop diabetes and it＇ s complications happen.
作者
张艳荷
曾志强
黄建生
杨元生
ZHANG Yan-he;ZENG Zhi-qiang;HUANG Jian-sheng(General Medicine Department, the Community Sanitation Service Center of Humen Town, Dongguan, Guangdong 523900, Chin)
出处
《中华全科医学》
2018年第7期1125-1127,共3页
Chinese Journal of General Practice
基金
广东省东莞市科技计划项目(20131051010258
2016105101206)
关键词
糖尿病前期
糖耐量减低
空腹血糖受损
糖调节受损
危险因素
Prediabetes
Impaired glucose tolerance
Impaired fasting glucose
Impaired glucose regulation
Risk factor
作者简介
通信作者：曾志强，E-mail：lubee520@126．com
