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综合疗法治疗强直性脊柱炎临床研究

Clinical Study of Combined Therapy for Ankylosing Spondylitis
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摘要 目的:探讨综合疗法治疗强直性脊柱炎(AS)临床效果。方法:86例AS患者按随机数字法分为观察组和对照组,各43例。2组均给予休息、营养、功能锻炼等常规治疗。对照组加用柳氮磺胺吡啶片(0.25g/片),4片/次,2次/d,双氯芬酸钠缓释片(100mg/片)1片/次,1杉d。观察组加用中药内服治疗及针刺治疗。2组疗程均为1个月,连用3个疗程进行效果评价。结果:(1)2组显效率39.5%(17/43)vs20.9%(9/43),有效率58.1%(25/43)vs60.5%(26/43),观察组明显优于对照组(P〈0.05);(2)观察组总有效率为97.7%(42/43),对照组为81.4%(35/43),观察组总有效率优于对照组(P〈0.05);(3)2组治疗后红细胞沉降率(ESR)及超敏c反应蛋白(hs-CRP)浓度均明显下降,观察组下降更明显,明显优于对照组(P〈0.01)。结论:综合疗法治疗ASl临床效果显著,可以明显改善患者临床症状,降低ESR、hs-CRP等炎性指标。 Objective:To investigate the clinical effect of combined therapy on ankylosing spondylitis. Methods: 86 patients with an- kylosing spondylitis were divided into observation group and control group by random number method, 43 cases each. Two groups were given rest, nutrition, functional exercises and other conventional treatment. The control group was treated with sulfasalazine ( O. 25 g/tab- lets), 4 tablets/times, 2 times/day, Diclofenac Sodium Sustained Release Tablets (100 mg/tablets), 1 tablets/times, 1 times/d. The observation group was treated with traditional Chinese medicine and acupuncture treatment. The two groups were treated for 1 months, and 3 courses were used to evaluate the effect. Results: ①The effective rate of the two groups was 39.5 % ( 17/43 ) vs 20.9% (9/43), the ef- fective rate was 58.1% (25/43) vs 60.5% (26/43), and the observation group was significantly better than the control group( P 〈 0. 05 ) ; ②The total effective rate was 97.7% (42/43) in the observation group and 81.4% ( 35/43 ) in the control group. The total effective rate of the observation group was better than that of the control group ( P 〈 0.05 ) ; ③The erythrocyte sedimentation rate (ESR) and the hypersensitive C reactive protein( hs -CRP) concentration in the two groups after treatment decreased significantly, and the observation group decreased significantly, significantly better than the control group( P 〈 0.01 ). Conclusion: Comprehensive treatment of ankylo- sing spondylitis clinical effect is significant, can significantly improve the clinical symptoms of patients, reduce ESR, hs - CRP and other inflammatory indexes.
作者 衡墩前 周卫星 HENG Dun - qian ,ZHOU Wei - xing(TCM hospital of Xinyi city, Xinyi , Jiangsu22140)
出处 《中国伤残医学》 2018年第9期7-9,共3页 Chinese Journal of Trauma and Disability Medicine
关键词 强直性脊柱炎 综合疗法 中药 针刺 Ankylosing spondylitis Combined modality therapy Chinese medicine Acupuncture
作者简介 衡墩前,中医学本科,骨伤科副主任中医师,研究方向:颈肩腰腿疼痛综合治疗、四肢骨折保守治疗,单位:江苏省新沂市中医医院,地址:江苏省新沂市钟吾路80号,邮编:221400,手机:13952292883,邮箱348107249@qq.com;通讯作者
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