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microRNA在甲状腺癌中的研究进展 被引量:7

Research progress of microRNA in thyroid cancer
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摘要 甲状腺癌是最常见的内分泌系统恶性肿瘤,在全球范围内其发病率呈逐年上升趋势,已受到医务工作者的广泛关注。目前其病因仍不十分清楚,已有研究报道甲状腺癌的发病受性别、年龄、地域、种族差异等多种因素的影响,其病因主要包括:电离辐射、碘摄取过多或过少、遗传因素等。甲状腺癌由来源于甲状腺滤泡细胞和滤泡旁C细胞2种, microRNA(miRNA)is a kind of endogenous non-coding single-stranded molecule RNA.The generation process is associated with the production of small interfering RNAs.In recent years,it has been found that different miRNA express in different pathological types of thyroid cancer both at home and abroad,suggesting that many miRNAs may play important roles in occurrence,development,invasion and migration of thyroid cancer,which can be new opportunities in diagnosis,treatment and prognosis of thyroid cancer.In this paper,we will review the recent advances in the study of the relationship between microRNA and thyroid cancer.
出处 《临床耳鼻咽喉头颈外科杂志》 CAS 北大核心 2018年第5期397-400,共4页 Journal of Clinical Otorhinolaryngology Head And Neck Surgery
基金 湖北省教育厅重点项目(No:D20141205)
关键词 甲状腺肿瘤 MICRORNA 进展 thyroidcarcinoma microRNA progress
作者简介 通信作者:鲁明骞,E-mail:lumingqian001@163.com
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  • 1吴传勇,薛剑,娄加陶.microRNA在肺癌诊断、治疗及预后判断中的作用[J].上海交通大学学报(医学版),2011,31(3):368-372. 被引量:7
  • 2王笑春,易凡,支凯林.甲状腺髓样癌不同手术方式对预后影响(附46例报告)[J].临床军医杂志,2006,34(3):305-306. 被引量:2
  • 3Ghildiyal M,Zamore PD.Small silencing RNAs:an expanding univmse[J].Nat Rev Genet,2009,10(2):94-108.
  • 4Menon MP,Khan A.Micro RNAs in thyroid neoplasms:molecular diagnostic and therapeutic implications[J].J Clin Pathol,2009,62(11):978-985.
  • 5Chou CK,Chen RF,Chou FF,et al.MiR-146b is highly expressed in adult papillary thyroid carcinomas with high risk features including extrathyroidal invasion and the BRAF(V600E) mutation[J].Throid,2010,20(5):489-494.
  • 6Braun J,Hüttelmaier S.Pathogenic mechanisms of deregulated microRNAexpression in thyroid carcinomas of follicular origin[J].Thyroid Res,2011,4(Suppl 1):S1.
  • 7Kondo T,Ezzat S,Asa SL,et al.Pathogenetic mechanism in thyroid follicular-cell neoplasia[J].Nat Rev Cancer,2006,6 (4):292-306.
  • 8Schmid KW.Molecular pathology of thyroid tumors[J].Patholoqe,2010,31(Suppl 2):229-233.
  • 9Menon MP,Khan A.Micro RNAs in thyroid neoplasms molecular diagnostic and therapeutic implications[J].J Clin Pathol,2009,62(11):978-985.
  • 10Braun J,Hoang-Vu C,Dralle H,et al.Down regulation of microRNAs directs the EMT and invasive potential of anaplastic thyroid carcinomas[J].Oncogene,2010,29(29):4237-4244.

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