摘要
目的研究裸花紫珠(Callicarpa nudiflora Hook.)正丁醇部位的化学成分。方法利用硅胶、ODS、Sephadex LH-20柱色谱、制备液相色谱等方法进行分离纯化,根据波谱数据分析和文献资料鉴定化合物的结构。结果从裸花紫珠正丁醇部位分离得到9个化合物,分别鉴定为:6-O-caffeoyl ajugol(1),leucosceptoslde A(2),6-O-咖啡酰-β-D-葡萄糖(3),nudifloside(4),木犀草素-7-O-葡萄糖苷(5),槲皮素3'-O-β-D-葡萄糖苷(6),cistaneside C(7),毛蕊花糖苷(8)和syringalide A 3'-α-L-rhamnopyranoside(9)。结论化合物1,2,6,7,9为首次从裸花紫珠中分离得到。
OBJECTIVE To study the chemical constituents of Callicarpa nudiflora. METHODS The chemical constituents were isolated and purified by column chromatography on silica gel, ODS, Sephadex LH-20 and MPLC. Their structures were elucidated by spectroscopic evidence and compared with those in literature. RESULTS Nine compounds were isolated and identified as 6-O-caffeoyl ajugol（1）, leucosceptoslde A（2）, 6-O-caffeoly-β-glucose（3）, nudifloside（4）, luteolin-7-O-glucoside（5）, quercetin 3′-O-β-D-glucoside（6）, cistaneside C（7）, acteoside（8）, and syringalide A 3′-α-L-rhamnopyranoside （9）. CONCLUSION Compounds 1, 2, 6, 7, and 9 are isolated from this plant for the first time.
出处
《中国药学杂志》
CAS
CSCD
北大核心
2017年第22期1983-1987,共5页
Chinese Pharmaceutical Journal
基金
国家自然科学基金资助项目(81373955)
江西省自然科学基金资助项目(20142BAB205085)
作者简介
王杰，男，硕士研究生研究方向：中药活性成分及质量标准研究;通讯作者：罗跃华，男，主任中药师研究方向：中药活性成分及质量标准研究Tel：（0791）88158689E-mail：emailluo@sohu．com
